ChemicalBook > CAS DataBase List > BMS-502
BMS-502
- Product Name
- BMS-502
- CAS No.
- 2407854-18-4
- Chemical Name
- BMS-502
- Synonyms
- BMS-502;BMS-502 (Compound 22);BMS-502（SCHEMBL21830991）;8-(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)-5-methyl-7-nitro-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile
- CBNumber
- CB513765779
- Formula Weight
- 0
- MOL File
- 2407854-18-4.mol
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BMS-502 Property
- form
- Solid
- color
- Light yellow to yellow
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BMS-502 Chemical Properties,Usage,Production
Definition
BMS-502 is a dual DGKα and ζ inhibitor. BMS-502 demonstrated dose-dependent immune stimulation in the mouse OT-1 model, setting the stage for a drug discovery program. BMS-502 demonstrated substantial inhibitory activity against DGKs α, ζ and ι[1].
References
[1] Louis Chupak* and Susan Wee. “Discovery of Potent, Dual-Inhibitors of Diacylglycerol Kinases Alpha and Zeta Guided by Phenotypic Optimization.” ACS Medicinal Chemistry Letters 14 7 (2023): 929–935.
BMS-502 Preparation Products And Raw materials
Raw materials
Preparation Products
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BMS-502 Suppliers
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View Lastest Price from BMS-502 manufacturers
Hubei Chuchang Biotech Co., Ltd.
- Product
- BMS-502 2407854-18-4
- Price
- US $0.00-0.00/MG
- Min. Order
- 1MG
- Purity
- 98
- Supply Ability
- 100G
- Release date
- 2024-04-17