harzianic acid

Product Name: harzianic acid
CAS No.: 157148-06-6
Chemical Name: harzianic acid
Synonyms: harzianic acid;2-Pyrrolidinepropanoic acid, α-hydroxy-4-[(2E,4E)-1-hydroxy-2,4-octadien-1-ylidene]-1-methyl-α-(1-methylethyl)-3,5-dioxo-, (αS,2S,4Z)-
CBNumber: CB51386230
Molecular Formula: C19H27NO6
Formula Weight: 365.42
MOL File: 157148-06-6.mol

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harzianic acid Property

Melting point:: 85-86 °C(Solv: ethyl acetate (141-78-6))
Boiling point:: 619.6±55.0 °C(Predicted)
Density: 1.225±0.06 g/cm3(Predicted)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 3.75±0.32(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: AGR0000779
Product name: HARZIANIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $499.46
Updated: 2021/12/16

Arctom

Product number: CFN00118
Product name: Harzianicacid
Packaging: 5mg
Price: $488
Updated: 2021/12/16

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harzianic acid Chemical Properties,Usage,Production

Description

Harzianic acid is a Trichoderma secondary metabolite. Harzianic acid shows plant growth promotion activity. 3. Harzianic acid has antifungal activity and antibiotic activity against Pythium irregulare, Sclerotinia sclerotiorum, and Rhizoctonia solani.

Uses

Harzianic acid, a tetramic acid derivative, with activity of antimicrobial, antibiofilm formation and biofilm disaggregation. Harzianic acid interferes with biofilm formation by limiting bacterial iron availability. Harzianic acid is also a selective inhibitor of Acetohydroxyacid synthase (AHAS), the first enzyme in the branched-chain amino acid biosynthetic pathway. Harzianic acid can used for herbicide and fungicide[1][2].

target

Antifection

References

[1] De Filippis A, et al. Antimicrobial activity of harzianic acid against Staphylococcus pseudintermedius. Nat Prod Res. 2021 Dec;35(23):5440-5445. DOI:10.1080/14786419.2020.1779714
[2] Xie L, et al. Harzianic Acid from Trichoderma afroharzianum Is a Natural Product Inhibitor of Acetohydroxyacid Synthase. J Am Chem Soc. 2021 Jun 16:10.1021/jacs.1c03988. DOI:10.1021/jacs.1c03988. doi: 10.1021/jacs.1c03988

harzianic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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harzianic acid Suppliers

China 6 United States 2 Global 8

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 6905
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Zhejiang Huida Biotech Co., LTD

Tel: 0571-0571-89903882 15990081639
Email: sunshixuan@huidabiotech.com
Country: China
ProdList: 3705
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

157148-06-6, harzianic acidRelated Search:

harzianic acid 3-Pyrrolidin-2-yl-propionic acid 2-ISOPROPYL-5-OXOHEXANOICACID 1-METHYL-PYRROLIDINE-2,4-DIONE 2,4-Pyrrolidinedione 3,5,7-Nonatrien-2-one 2-HEXANONE, 3-AMINO-5-METHYL- 5-(2-HYDROXY-ETHYL)-PYRROLIDIN-2-ONE

harzianic acid

2-Pyrrolidinepropanoic acid, α-hydroxy-4-[(2E,4E)-1-hydroxy-2,4-octadien-1-ylidene]-1-methyl-α-(1-methylethyl)-3,5-dioxo-, (αS,2S,4Z)-

157148-06-6