BMS453

ChemicalBook > CAS DataBase List > BMS453

Product Name: BMS453
CAS No.: 166977-43-1
Chemical Name: BMS453
Synonyms: BMS453;BMS-189453 (BMS189453;(E)-4-[2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid;(E)-4-[2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid;4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoicacid;Benzoic acid, 4-[(1E)-2-(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-;Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X receptors,BMS189453,arrest,cell,RARα,Retinoic acid receptors
CBNumber: CB51387459
Molecular Formula: C27H24O2
Formula Weight: 380.48
MOL File: 166977-43-1.mol

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BMS453 Property

Boiling point:: 560.9±50.0 °C(Predicted)
Density: 1.167±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: soluble10mg/mL, clear
form: powder
pka: 4.27±0.10(Predicted)
color: white to beige

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1149
Product name: BMS-189453
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $132
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1149
Product name: BMS-189453
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $535
Updated: 2024/03/01

Cayman Chemical

Product number: 19076
Product name: BMS 453
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 19076
Product name: BMS 453
Purity: ≥98%
Packaging: 5mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 19076
Product name: BMS 453
Purity: ≥98%
Packaging: 10mg
Price: $178
Updated: 2024/03/01

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BMS453 Chemical Properties,Usage,Production

Uses

BMS 453 is a synthetic retinoid and RARβ antagonist which also displays antagonist acitivity in RARα.

Definition

ChEBI: BMS-453 is a member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer). It is a potent retinoic acid receptor gamma (RARbeta) agonist that acts as an antagonist against RARalpha and RARgamma. It has a role as a retinoic acid receptor beta agonist, a retinoic acid receptor gamma antagonist, a retinoic acid receptor alpha antagonist and a teratogenic agent. It is a member of dihydronaphthalenes, a member of benzoic acids and a stilbenoid.

BMS453 Preparation Products And Raw materials

Raw materials

Preparation Products

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166977-43-1, BMS453Related Search:

BMS453

4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoicacid

(E)-4-[2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid

BMS-189453 (BMS189453

(E)-4-[2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid

Benzoic acid, 4-[(1E)-2-(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-

Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X receptors,BMS189453,arrest,cell,RARα,Retinoic acid receptors

166977-43-1