Siltenzepine

Product Name: Siltenzepine
CAS No.: 98374-54-0
Chemical Name: Siltenzepine
Synonyms: Siltenzepine;8-Chlor-5,10-dihydro-5--11H-dibenzo<1,4>-diazepin-11-on;11H-Dibenzo[b,e][1,4]diazepin-11-one, 5-[2-[bis(2-hydroxyethyl)amino]acetyl]-8-chloro-5,10-dihydro-
CBNumber: CB51402444
Molecular Formula: C19H20ClN3O4
Formula Weight: 389.83
MOL File: 98374-54-0.mol

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Siltenzepine Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0012485
Product name: SILTENZEPINE
Purity: 95.00%
Packaging: 5MG
Price: $502.35
Updated: 2021/12/16

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Siltenzepine Chemical Properties,Usage,Production

Uses

Siltenzepine (AWD 26-06 free base) is an antagonist of mAChR with anti-acid activity, which can be used in peptic ulcers research. Siltenzepine exhibits rapidly but incompletely absorbed characterastic in rats (po)[1][2].

in vivo

Siltenzepine (po) exhibits short distribution (t1/2 alpha=37 min) followed by a middle-long elimination (t1/2 beta=14 h) in rats^[1].

References

[1] Pfeifer S, et al. Biotransformation und Pharmakokinetik von AWD 26-06, 8-Chlor-5,10-dihydro-5-[bis(2-hydroxyethyl)aminoacetyl]-11H- dibenzo[d,c][1,4]diazepin-11-on-hydrochlorid an der Ratte [Biotransformation and pharmacokinetics of AWD 26-06, 8-chloro-5,10-dihydro-5-[bis(2-hydroxyethyl)aminoacetyl]-11H-dibenzo[d, c][1,4]diazepin-11-one hydrochloride in the rat]. Pharmazie. 1990 Jul;45(8):603-7. German. PMID:2080209
[2] Trausch B, et al. The biliary and renal elimination of the new muscarinic-1-antagonist AWD 26-06 in volunteers with T-tube after cholecystectomy. Int J Clin Pharmacol Ther Toxicol. 1992 Nov;30(11):508-9. PMID:1490811

Siltenzepine Preparation Products And Raw materials

Raw materials

Preparation Products

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Siltenzepine Suppliers

China 5 United States 4 Global 9

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-85201366 18938635012
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TargetMol Chemicals Inc.

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Beijing Jin Ming Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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Biosynth Biological Technology (Suzhou) Co Ltd

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Adooq Bioscience LLC

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TargetMol Chemicals Inc.

Tel: +17819995354
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Country: United States
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
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Country: United States
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98374-54-0, SiltenzepineRelated Search:

2-AMINO-4-CHLORODIPHENYLAMINE N-(2-aminophenyl)-2-(diethylamino)acetamide N1-(2-AMINOPHENYL)-N2,N2-DIMETHYLGLYCINAMIDE 2-AMINO-N-(3-CHLOROPHENYL)BENZAMIDE 5,10-DIHYDRO-DIBENZO[B,E][1,4]DIAZEPIN-11-ONE 2-(2-HYDROXYETHYLAMINO)-N-(4-CHLOROPHENYL)ACETAMIDE 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one N-(2-aminophenyl)-N-methyl-N-phenylamine 2-diethylamino-N,N-diphenyl-acetamide Siltenzepine

Siltenzepine

8-Chlor-5,10-dihydro-5-<bis(2-hydroxyethyl)aminoacetyl>-11H-dibenzo<b,e><1,4>-diazepin-11-on

11H-Dibenzo[b,e][1,4]diazepin-11-one, 5-[2-[bis(2-hydroxyethyl)amino]acetyl]-8-chloro-5,10-dihydro-

98374-54-0