ACETYL-L-CARNITINE

ACETYL-L-CARNITINE Property

solubility 

DMF, DMSO, ethanol

form 

Solid

color 

White to off-white

Appearance

white solid

LogP

-4.149 (est)

Hazard and Precautionary Statements (GHS)

ACETYL-L-CARNITINE Chemical Properties,Usage,Production

Description

Acetylcarnitine is an ester of the amino acid carnitine with an acetyl group, the first representative of short-chain acyl-carnitines.

The product is used primarily as a control for MS/MS.

Acetyl-L-carnitine, like other carnitines, is involved in the transport of fatty acids into mitochondria for β-oxidation and energy production. Acetylcarnitine easily penetrates the blood-brain barrier (BBB) ​​and has an effect on the central nervous system (CNS), is used as a neuroprotector, a neurotrophic drug, and has a cholinomimetic effect. It is also a key molecule in the study of aging and related metabolic processes, due to its involvement in lipid metabolism and the production of acetyl-CoA, a central metabolite in many biosynthetic and energy pathways.

Uses

Acetylcarnitine is an endogenous metabolite.

Definition

ChEBI: O-acetylcarnitine is an O-acylcarnitine having acetyl as the acyl substituent. It has a role as a human metabolite. It is functionally related to an acetic acid. It is a conjugate base of an O-acetylcarnitinium.