ChemicalBook > CAS DataBase List > 1-Hydroxymethyl-1,2,4-triazole

1-Hydroxymethyl-1,2,4-triazole

Product Name
1-Hydroxymethyl-1,2,4-triazole
CAS No.
74205-82-6
Chemical Name
1-Hydroxymethyl-1,2,4-triazole
Synonyms
1,2,4-Triazole-1-methanol;1,2,4-triazol-1-ylmethanol;1H-1,2,4-Triazole-1-methanol;1-Hydroxymethyl-1,2,4-triazole;(1H-1,2,4-Triazol-1-yl)Methanol
CBNumber
CB51453163
Molecular Formula
C3H5N3O
Formula Weight
99.09
MOL File
74205-82-6.mol
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1-Hydroxymethyl-1,2,4-triazole Property

Melting point:
70-71℃
Boiling point:
290℃
Density 
1.42
Flash point:
129℃
storage temp. 
Inert atmosphere,Room Temperature
pka
11.58±0.10(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T3797
Product name
(1H-1,2,4-Triazol-1-yl)methanol
Purity
min. 98.0 %
Packaging
1G
Price
$157
Updated
2025/07/31
Oakwood
Product number
180008
Product name
1H-1,2,4-Triazol-1-ylmethanol
Purity
90%
Packaging
100mg
Price
$175
Updated
2021/12/16
AK Scientific
Product number
1023AL
Product name
(1H-1,2,4-Triazol-1-yl)methanol
Packaging
25g
Price
$200
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0079537
Product name
1H-1,2,4-TRIAZOLE-1-METHANOL
Purity
95.00%
Packaging
5G
Price
$909.56
Updated
2021/12/16
Alichem
Product number
74205826
Product name
(1H-1,2,4-Triazol-1-yl)methanol
Packaging
100g
Price
$294
Updated
2021/12/16
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1-Hydroxymethyl-1,2,4-triazole Chemical Properties,Usage,Production

Uses

1-Hydroxymethyl-1,2,4-triazole is useful in the synthesis of novel triazole compounds that have anti-fungal properties.

Synthesis

288-88-0

50-00-0

74205-82-6

Step 1. Preparation of (1H-1,2,4-triazol-1-yl)methanol 1H-1,2,4-triazole (7.04 g, 102 mmol) was mixed with paraformaldehyde (3.06 g, 102 mmol) and catalytic amount of triethylamine was added. The mixture was heated to a molten state (140°C) and stirred at this temperature for 0.5 hours. After completion of the reaction, the reaction mixture was cooled to 30 °C to give a white solid product (9.0 g, 89% yield).

References

[1] Heterocyclic Communications, 2001, vol. 7, # 6, p. 577 - 582
[2] Phosphorus and Sulfur and the Related Elements, 1987, vol. 33, p. 41 - 52
[3] Tetrahedron, 2010, vol. 66, # 47, p. 9145 - 9150
[4] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980, vol. 16, # 2, p. 189 - 194
[5] Khimiya Geterotsiklicheskikh Soedinenii, 1980, vol. 16, # 2, p. 251 - 256

1-Hydroxymethyl-1,2,4-triazole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-Hydroxymethyl-1,2,4-triazole manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
1-Hydroxymethyl-1,2,4-triazole 74205-82-6
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%min
Supply Ability
1000kg
Release date
2025-06-13
Honest Joy Holdings Limited
Product
1,2,4-triazol-1-ylmethanol 74205-82-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99.2%
Supply Ability
100 tons
Release date
2022-01-14
Career Henan Chemical Co
Product
1-Hydroxymethyl-1,2,4-triazole 74205-82-6
Price
US $1.00/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
100KG
Release date
2019-07-31