ChemicalBook > CAS DataBase List > 1-(2-bromo-5-methoxy-phenyl)ethanone

1-(2-bromo-5-methoxy-phenyl)ethanone

Product Name
1-(2-bromo-5-methoxy-phenyl)ethanone
CAS No.
6342-63-8
Chemical Name
1-(2-bromo-5-methoxy-phenyl)ethanone
Synonyms
3-Acetyl-4-bromoanisole;2’-Bromo-5’-methoxyacetophenone;1-(2-bromo-5-methoxy-phenyl)ethanone;ETHANONE 1-(2-BROMO-5-METHOXYPHENYL)-;2′-Bromo-5′-methoxyacetophenone, CAS 6342-63-8;1-(2-Bromo-5-methoxyphenyl)ethan-1-one, 3-Acetyl-4-bromoanisole
CBNumber
CB51458188
Molecular Formula
C9H9BrO2
Formula Weight
229.07
MOL File
6342-63-8.mol
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1-(2-bromo-5-methoxy-phenyl)ethanone Property

Melting point:
102°C
Boiling point:
102 °C(Press: 0.4 Torr)
Density 
1.421±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
liquid
color 
Yellow
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Safety

HS Code 
2914790090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A168805
Product name
3-Acetyl-4-bromoanisole
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
A168805
Product name
3-Acetyl-4-bromoanisole
Packaging
1g
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
2617-9-Y1
Product name
2'-Bromo-5'-methoxyacetophenone
Packaging
1g
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB70339
Product name
2'-Bromo-5'-methoxyacetophenone
Packaging
5G
Price
$125
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB70339
Product name
2'-Bromo-5'-methoxyacetophenone
Packaging
2g
Price
$70
Updated
2021/12/16
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1-(2-bromo-5-methoxy-phenyl)ethanone Chemical Properties,Usage,Production

Preparation

Obtained by action of pyridinium chlorochromate with 1-(2-bromo-5-methoxy) ethanol.

Synthesis

71095-23-3

6342-63-8

General procedure for the synthesis of 1-(2-bromo-5-methoxyphenyl)ethan-1-ol from 1-(2-bromo-5-methoxyphenyl)ethanone: To a solution of 1-(2-bromo-5-methoxyphenyl)ethan-1-ol (3.8 g, 16.5 mmol) in methylene chloride (100 mL) was added pyridinium chlorochromate (PCC, 8.4 g, 33.0 mmol). The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the mixture was filtered and the filtrate was concentrated. The crude product was purified by silica gel fast column chromatography with the eluent of petroleum ether/ethyl acetate (5:1) to afford 1-(2-bromo-5-methoxyphenyl)ethanone (3.6 g, 95% yield) as an off-white solid.1H NMR (300 MHz, CDCl3) δ 7.45 (d, 1H), 6.96 (d, 1H), 6.82 (dd, 1H) 4.38 (q, 2H), 3.80 (s, 3H), 2.62 (s, 3H).

References

[1] Organic Letters, 2012, vol. 14, # 2, p. 628 - 631
[2] ACS Medicinal Chemistry Letters, 2012, vol. 3, # 7, p. 550 - 554
[3] Patent: WO2013/22740, 2013, A2. Location in patent: Paragraph 0393; 0395
[4] Journal of Organic Chemistry, 2014, vol. 79, # 5, p. 2059 - 2074
[5] Synthetic Communications, 2014, vol. 44, # 14, p. 2076 - 2087

1-(2-bromo-5-methoxy-phenyl)ethanone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(2-bromo-5-methoxy-phenyl)ethanone Suppliers

China 48 India 1 United Kingdom 2 United States 7 Global 58
Nanjing Norris-Pharm Technology Co., Ltd
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18652989687
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China
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9ding chemical ( Shanghai) Limited
Tel
4009209199
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86-021-52271987
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sales@9dingchem.com
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China
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Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
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product02@bidepharm.com
Country
China
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40000
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Xinyanhe Pharmatech Co.,Ltd
Tel
0519-85252752 15366845260
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86-0519-85683352
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Zhengzhou kangnuochenrui Chemical Technology Co.,Ltd
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18210788515; 18210788515
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
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parabiochem
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Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
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022-23754520
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China
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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China
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9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
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+86 (21) 52271987
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6342-63-8, 1-(2-bromo-5-methoxy-phenyl)ethanoneRelated Search:


  • 1-(2-bromo-5-methoxy-phenyl)ethanone
  • 1-(2-Bromo-5-methoxyphenyl)ethan-1-one, 3-Acetyl-4-bromoanisole
  • 3-Acetyl-4-bromoanisole
  • ETHANONE 1-(2-BROMO-5-METHOXYPHENYL)-
  • 2’-Bromo-5’-methoxyacetophenone
  • 2′-Bromo-5′-methoxyacetophenone, CAS 6342-63-8
  • 6342-63-8