5,7,8-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one

5,7,8-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one Property

Melting point:

247-248 °C

Boiling point:

592.5±50.0 °C(Predicted)

Density 

1.654±0.06 g/cm3(Predicted)

pka

6.67±0.40(Predicted)

form 

Solid

color 

Light yellow to yellow

InChI

InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)12-6-10(18)13-9(17)5-11(19)14(20)15(13)21-12/h1-6,16-17,19-20H

InChIKey

NXHQVROAKYDSNW-UHFFFAOYSA-N

SMILES

C1(C2=CC=C(O)C=C2)OC2=C(O)C(O)=CC(O)=C2C(=O)C=1

Hazard and Precautionary Statements (GHS)

5,7,8-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one Chemical Properties,Usage,Production

Chemical Properties

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Hedyotis diffusa Willd; Scutellaria barbata.

Uses

Isoscutellarein is a flavonoid compound that can be isolated from Wissadula periplocifolia (L.) C. Presl (Malvaceae)[1]

Definition

ChEBI: A tetrahydroxyflavone that is apigenin with an extra hydroxy group at position 8.

References

[1] Teles YC, et al. New Sulphated Flavonoids from Wissadula periplocifolia (L.) C. Presl (Malvaceae). Molecules. 2015 Nov 9;20(11):20161-72. DOI:10.3390/molecules201119685
[2] Yang H, et al. New bioactive polyphenols from Theobroma grandiflorum ("cupua?u"). J Nat Prod. 2003;66(11):1501-1504. DOI:10.1021/np034002j
[3] Lawrence J.P, et al. Isoscutellarein and hypolaetin 8-glucuronides from the liverwort Marchantia berteroana.