ChemicalBook > CAS DataBase List > 5-amino-1,2-dihydropyrazol-3-one

5-amino-1,2-dihydropyrazol-3-one

Product Name
5-amino-1,2-dihydropyrazol-3-one
CAS No.
28491-52-3
Chemical Name
5-amino-1,2-dihydropyrazol-3-one
Synonyms
5-amino-1,2-dihydro-3H-pyrazol-3-one;-5-one;5-Amino-1H-pyrazol-3(2H);3-Amino-3-pyrazolin-5-one;3-Amino-1,2-dihydropyrazoL;5-AMino-1H-pyrazol-3(2H)-one;5-Amino-3-hydroxy-1H-pyrazole;3-Amino-1,2-dihydropyrazol-5-one;5-amino-1,2-dihydropyrazol-3-one;3H-Pyrazol-3-one,5-amino-1,2-dihydro-
CBNumber
CB51463409
Molecular Formula
C3H5N3O
Formula Weight
99.09
MOL File
28491-52-3.mol
More
Less

5-amino-1,2-dihydropyrazol-3-one Property

Melting point:
204℃
Density 
1.301
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
8.31±0.70(Predicted)
Appearance
Light brown to brown Solid
InChI
InChI=1S/C3H5N3O/c4-2-1-3(7)6-5-2/h1H,(H4,4,5,6,7)
InChIKey
QZBGOTVBHYKUDS-UHFFFAOYSA-N
SMILES
N1C(N)=CC(=O)N1
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Synthonix
Product number
A0899
Product name
5-Amino-1,2-dihydropyrazol-3-one
Purity
97%
Packaging
1g
Price
$15
Updated
2026/05/06
Synthonix
Product number
A0899
Product name
5-Amino-1,2-dihydropyrazol-3-one
Purity
97%
Packaging
5g
Price
$23
Updated
2026/05/06
Synthonix
Product number
A0899
Product name
5-Amino-1,2-dihydropyrazol-3-one
Purity
97%
Packaging
10g
Price
$30
Updated
2026/05/06
Synthonix
Product number
A0899
Product name
5-Amino-1,2-dihydropyrazol-3-one
Purity
97%
Packaging
25g
Price
$70
Updated
2026/05/06
Synthonix
Product number
A0899
Product name
5-Amino-1,2-dihydropyrazol-3-one
Purity
97%
Packaging
100g
Price
$210
Updated
2026/05/06
More
Less

5-amino-1,2-dihydropyrazol-3-one Chemical Properties,Usage,Production

Synthesis

37832-55-6

28491-52-3

General procedure for the synthesis of 5-amino-1H-pyrazol-3-one from 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid: to a reaction flask was added toluene (500 mL), triethylamine (138.6 mL, 1.0 mol, 2.0 eq), and 5-hydroxy-4-carboxylic acid ester (64 g, 0.5 mol, 1.0 eq) made in step (1). After raising the temperature of the reaction system to 80°C, diphenylphosphoryl azide (DPPA, 162.5 mL, 0.75 mol, 1.5 eq) was slowly added and stirred continuously for 5 hours at this temperature. After the reaction was completed, the system was cooled to room temperature. The reaction solution was concentrated, 500 mL of saturated aqueous ammonium chloride solution was added, the precipitated white precipitate was collected and dried to give 5-amino-1,2-dihydro-pyrazol-3-one 44.7 g in 90% yield.

References

[1] Patent: CN105541719, 2016, A. Location in patent: Paragraph 0028; 0030

5-amino-1,2-dihydropyrazol-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-amino-1,2-dihydropyrazol-3-one Suppliers

Changzhou Mailekang Pharmaceutical Technology Co., Ltd.
Tel
0519-69655553 13961137915
Email
mlksales@126.com
Country
China
ProdList
62
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
13611835272 13611835272
Fax
021-5161 3951
Email
mmwang@sunwaypharm.com
Country
China
ProdList
44108
Advantage
58
Dancheng Huatai Biotechnology Co., Ltd.
Tel
13482210809 13482210809
Email
hli@3wpharm.com
Country
China
ProdList
334
Advantage
58
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7241
Advantage
62
Acorn PharmaTech Co., Ltd.
Tel
025-58395930
Fax
025-5861-9182
Email
sales@acornpharma.com
Country
China
ProdList
982
Advantage
60
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq:2817624287
Email
983544897@qq.com
Country
China
ProdList
9340
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
29974
Advantage
65
More
Less

View Lastest Price from 5-amino-1,2-dihydropyrazol-3-one manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
5-amino-1,2-dihydropyrazol-3-one 28491-52-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
2000
Release date
2025-09-04
Honest Joy Holdings Limited
Product
3-Amino-1,2-dihydropyrazol-5-one 28491-52-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99.5%
Supply Ability
100 tons
Release date
2022-01-14
Career Henan Chemical Co
Product
5-amino-1,2-dihydropyrazol-3-one 28491-52-3
Price
US $1.00/KG
Min. Order
1KG
Purity
96%
Supply Ability
500kg
Release date
2018-08-20

28491-52-3, 5-amino-1,2-dihydropyrazol-3-oneRelated Search:


  • 5-amino-1,2-dihydropyrazol-3-one
  • 3-Amino-1,2-dihydropyrazol-5-one
  • 3-Amino-3-pyrazolin-5-one
  • 5-Amino-3-hydroxy-1H-pyrazole
  • 5-Amino-1H-pyrazol-3(2H)
  • 5-AMino-1H-pyrazol-3(2H)-one
  • 3H-Pyrazol-3-one,5-amino-1,2-dihydro-
  • 3-Amino-1,2-dihydropyrazoL
  • -5-one
  • 5-amino-1,2-dihydro-3H-pyrazol-3-one
  • 28491-52-3