3-Chloro-4-hydroxy-5-nitropyridine
- Product Name
- 3-Chloro-4-hydroxy-5-nitropyridine
- CAS No.
- 31872-64-7
- Chemical Name
- 3-Chloro-4-hydroxy-5-nitropyridine
- Synonyms
- 5-Chloro-3-nitro-4-pyridinol;3-Chloro-5-nitro-4-pyridinol;4-Pyridinol, 3-chloro-5-nitro-;3-chloro-5-nitro-1H-pyridin-4-one;3-Chloro-4-hydroxy-5-nitropyridine;3-Chloro-4-hydroxy-5-nitropyridine ISO 9001:2015 REACH
- CBNumber
- CB51471190
- Molecular Formula
- C5H3ClN2O3
- Formula Weight
- 174.54
- MOL File
- 31872-64-7.mol
3-Chloro-4-hydroxy-5-nitropyridine Property
- Melting point:
- 263℃
- Boiling point:
- 339.3±37.0 °C(Predicted)
- Density
- 1.664±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- -1.56±0.38(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- ADE000441
- Product name
- 3-Chloro-5-nitropyridin-4-ol
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $463
- Updated
- 2023/06/20
- Product number
- C384780
- Product name
- 3-Chloro-5-nitropyridin-4-ol
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- C384780
- Product name
- 3-Chloro-5-nitropyridin-4-ol
- Packaging
- 250mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- OR952268
- Product name
- 3-Chloro-5-nitropyridin-4-ol
- Purity
- 95%
- Packaging
- 1g
- Price
- $310
- Updated
- 2021/12/16
- Product number
- 035145
- Product name
- 3-Chloro-5-nitropyridin-4-ol
- Packaging
- 500mg
- Price
- $61
- Updated
- 2021/12/16
3-Chloro-4-hydroxy-5-nitropyridine Chemical Properties,Usage,Production
Synthesis
5435-54-1
31872-64-7
General procedure for the synthesis of 3-chloro-4-hydroxy-5-nitropyridine from 4-hydroxy-3-nitropyridine: 3-nitropyridin-4-ol (8-a, 20 g, 142.76 mmol, 1 eq.) was dissolved in 50% aqueous acetic acid (250 mL) and reacted with the passage of chlorine gas for 20 h at room temperature. After completion of the reaction, the precipitate was collected by filtration and washed with distilled water. Intermediate 9-b (24 g, 97% yield) was finally obtained.
References
[1] Patent: WO2013/186332, 2013, A1. Location in patent: Page/Page column 51
[2] Patent: WO2013/186335, 2013, A1. Location in patent: Page/Page column 76
[3] Journal of Medicinal Chemistry, 2006, vol. 49, # 17, p. 5352 - 5362
[4] Patent: WO2009/108551, 2009, A2. Location in patent: Page/Page column 65-66
3-Chloro-4-hydroxy-5-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Chloro-4-hydroxy-5-nitropyridine manufacturers
- Product
- 3-Chloro-4-hydroxy-5-nitropyridine 31872-64-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-28
- Product
- 3-Chloro-4-hydroxy-5-nitropyridine 31872-64-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09