5-BROMO-2-CHLOROBENZALDEHYDE
- Product Name
- 5-BROMO-2-CHLOROBENZALDEHYDE
- CAS No.
- 189628-37-3
- Chemical Name
- 5-BROMO-2-CHLOROBENZALDEHYDE
- Synonyms
- 2-chloro-5-bromobenzaldehyde;Benzaldehyde, 5-broMo-2-chloro-;5-Bromo-2-chlorobenzaldehyde,98%;5-Bromo-2-chlorobenzaldehyde >5-BroMo-2-chlorobenzaldehyde, 97+%
- CBNumber
- CB51473280
- Molecular Formula
- C7H4BrClO
- Formula Weight
- 219.46
- MOL File
- 189628-37-3.mol
5-BROMO-2-CHLOROBENZALDEHYDE Property
- Melting point:
- 43-46℃
- Boiling point:
- 261℃
- Density
- 1.698
- Flash point:
- 112℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Sparingly), DMSO (Soluble, Heated), Methanol (Slightly, Sonicated)
- form
- Solid
- color
- Off-white to pale yellow
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C7H4BrClO/c8-6-1-2-7(9)5(3-6)4-10/h1-4H
- InChIKey
- DPKKRQAEYWOISP-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC(Br)=CC=C1Cl
Safety
- Hazard Codes
- Xi,E
- HS Code
- 2913000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B4756
- Product name
- 5-Bromo-2-chlorobenzaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $24
- Updated
- 2025/07/31
- Product number
- B4756
- Product name
- 5-Bromo-2-chlorobenzaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $68
- Updated
- 2025/07/31
- Product number
- B699463
- Product name
- 5-Bromo-2-chlorobenzaldehyde
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB33883
- Product name
- 5-Bromo-2-chlorobenzaldehyde
- Packaging
- 5G
- Price
- $50
- Updated
- 2021/12/16
- Product number
- OR6702
- Product name
- 5-Bromo-2-chlorobenzaldehyde
- Packaging
- 25g
- Price
- $61
- Updated
- 2021/12/16
5-BROMO-2-CHLOROBENZALDEHYDE Chemical Properties,Usage,Production
Chemical Properties
Appearance :white crystal powde
Uses
It finds its application as an intermediate in organic syntheses.
Synthesis
149965-40-2
189628-37-3
Example 2B Synthesis of 5-bromo-2-chlorobenzaldehyde: 18 mL (0.26 mol) of DMSO was dissolved in 64 mL of dichloromethane at -78 °C and 16.1 g (0.127 mol, 11.1 mL) of oxalyl chloride was slowly added. After 30 minutes of reaction, 13.1 g (59 mmol) of 2-chloro-5-bromobenzyl alcohol dissolved in 100 mL of chloroform was added dropwise. After continuing the reaction for 20 minutes, 40 mL of triethylamine was added, followed by slow warming of the reaction mixture to room temperature. Upon completion of the reaction, 50 mL of water was added and the mixture was extracted several times with ethyl acetate. The organic phases were combined and washed sequentially with 2N hydrochloric acid, water, saturated sodium bicarbonate solution and saturated sodium chloride solution. The organic phase was dried over magnesium sulfate and concentrated in vacuum. The resulting solid was further dried until a constant weight was reached under high vacuum. Yield: 12.7 g (94% yield). HPLC (Method 11): Rt = 4.65 min. MS (EI): m/z = 218 (M)+. 1H-NMR (300 MHz, CDCl3): δ = 7.32 (d, 1H), 7.65 (dd, 1H), 8.03 (d, 1H), 10.4 (s, 1H).
References
[1] Patent: US2006/25349, 2006, A1. Location in patent: Page/Page column 20
[2] Patent: US2007/99885, 2007, A1. Location in patent: Page/Page column 13-14
[3] Patent: CN107556276, 2018, A. Location in patent: Paragraph 0068; 0072-0073
[4] Patent: US2003/176506, 2003, A1
[5] Patent: WO2004/74270, 2004, A2. Location in patent: Page 364
5-BROMO-2-CHLOROBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BROMO-2-CHLOROBENZALDEHYDE manufacturers
- Product
- 5-BROMO-2-CHLOROBENZALDEHYDE 189628-37-3
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-11-28
- Product
- 5-Bromo-2-chlorobenzaldehyde 189628-37-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2024-01-04
- Product
- 5-BROMO-2-CHLOROBENZALDEHYDE 189628-37-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2018-08-06