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5-BROMO-2-CHLOROBENZALDEHYDE

Product Name
5-BROMO-2-CHLOROBENZALDEHYDE
CAS No.
189628-37-3
Chemical Name
5-BROMO-2-CHLOROBENZALDEHYDE
Synonyms
2-chloro-5-bromobenzaldehyde;Benzaldehyde, 5-broMo-2-chloro-;5-Bromo-2-chlorobenzaldehyde,98%;5-Bromo-2-chlorobenzaldehyde >5-BroMo-2-chlorobenzaldehyde, 97+%
CBNumber
CB51473280
Molecular Formula
C7H4BrClO
Formula Weight
219.46
MOL File
189628-37-3.mol
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5-BROMO-2-CHLOROBENZALDEHYDE Property

Melting point:
43-46℃
Boiling point:
261℃
Density 
1.698
Flash point:
112℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Sparingly), DMSO (Soluble, Heated), Methanol (Slightly, Sonicated)
form 
Solid
color 
Off-white to pale yellow
Water Solubility 
Slightly soluble in water.
InChI
InChI=1S/C7H4BrClO/c8-6-1-2-7(9)5(3-6)4-10/h1-4H
InChIKey
DPKKRQAEYWOISP-UHFFFAOYSA-N
SMILES
C(=O)C1=CC(Br)=CC=C1Cl
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Safety

Hazard Codes 
Xi,E
HS Code 
2913000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B4756
Product name
5-Bromo-2-chlorobenzaldehyde
Purity
>98.0%(GC)
Packaging
1g
Price
$24
Updated
2025/07/31
TCI Chemical
Product number
B4756
Product name
5-Bromo-2-chlorobenzaldehyde
Purity
>98.0%(GC)
Packaging
5g
Price
$68
Updated
2025/07/31
TRC
Product number
B699463
Product name
5-Bromo-2-chlorobenzaldehyde
Packaging
250mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB33883
Product name
5-Bromo-2-chlorobenzaldehyde
Packaging
5G
Price
$50
Updated
2021/12/16
Apolloscientific
Product number
OR6702
Product name
5-Bromo-2-chlorobenzaldehyde
Packaging
25g
Price
$61
Updated
2021/12/16
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5-BROMO-2-CHLOROBENZALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

Appearance :white crystal powde

Uses

It finds its application as an intermediate in organic syntheses.

Synthesis

149965-40-2

189628-37-3

Example 2B Synthesis of 5-bromo-2-chlorobenzaldehyde: 18 mL (0.26 mol) of DMSO was dissolved in 64 mL of dichloromethane at -78 °C and 16.1 g (0.127 mol, 11.1 mL) of oxalyl chloride was slowly added. After 30 minutes of reaction, 13.1 g (59 mmol) of 2-chloro-5-bromobenzyl alcohol dissolved in 100 mL of chloroform was added dropwise. After continuing the reaction for 20 minutes, 40 mL of triethylamine was added, followed by slow warming of the reaction mixture to room temperature. Upon completion of the reaction, 50 mL of water was added and the mixture was extracted several times with ethyl acetate. The organic phases were combined and washed sequentially with 2N hydrochloric acid, water, saturated sodium bicarbonate solution and saturated sodium chloride solution. The organic phase was dried over magnesium sulfate and concentrated in vacuum. The resulting solid was further dried until a constant weight was reached under high vacuum. Yield: 12.7 g (94% yield). HPLC (Method 11): Rt = 4.65 min. MS (EI): m/z = 218 (M)+. 1H-NMR (300 MHz, CDCl3): δ = 7.32 (d, 1H), 7.65 (dd, 1H), 8.03 (d, 1H), 10.4 (s, 1H).

References

[1] Patent: US2006/25349, 2006, A1. Location in patent: Page/Page column 20
[2] Patent: US2007/99885, 2007, A1. Location in patent: Page/Page column 13-14
[3] Patent: CN107556276, 2018, A. Location in patent: Paragraph 0068; 0072-0073
[4] Patent: US2003/176506, 2003, A1
[5] Patent: WO2004/74270, 2004, A2. Location in patent: Page 364

5-BROMO-2-CHLOROBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-CHLOROBENZALDEHYDE Suppliers

Changzhou Tianrui Pharmaceutical Technology Co., Ltd.
Tel
0519-85386832 13382812559
Fax
0519-85386832
Email
sales@cztrchem.com
Country
China
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Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
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9310
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66
Nanjing Tangzheng Biomedical Technology Co., Ltd
Tel
13016839191
Email
719086845@qq.com
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China
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TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Tel
022-60189726 18812034280
Fax
86-22-60979672
Email
188120342808@163.com
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China
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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Alfa Aesar
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400-6106006
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021-67582001/03/05
Email
saleschina@alfa-asia.com
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China
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
Fax
021-67121385
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Sales-CN@TCIchemicals.com
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China
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Ark Pharm, Inc.
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847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
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View Lastest Price from 5-BROMO-2-CHLOROBENZALDEHYDE manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
5-BROMO-2-CHLOROBENZALDEHYDE 189628-37-3
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-11-28
Nanjing Fred Technology Co., Ltd
Product
5-Bromo-2-chlorobenzaldehyde 189628-37-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2024-01-04
Career Henan Chemical Co
Product
5-BROMO-2-CHLOROBENZALDEHYDE 189628-37-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2018-08-06