ChemicalBook > CAS DataBase List > N,N''-BIS[3-(ETHYLAMINO)PROPYL]PROPANE-1,3-DIAMINE TETRAHYDROCHLORIDE
N,N''-BIS[3-(ETHYLAMINO)PROPYL]PROPANE-1,3-DIAMINE TETRAHYDROCHLORIDE
- Product Name
- N,N''-BIS[3-(ETHYLAMINO)PROPYL]PROPANE-1,3-DIAMINE TETRAHYDROCHLORIDE
- CAS No.
- 156886-85-0
- Chemical Name
- N,N''-BIS[3-(ETHYLAMINO)PROPYL]PROPANE-1,3-DIAMINE TETRAHYDROCHLORIDE
- Synonyms
- Diethylnorspermine HCl;N,N''-BIS[3-(ETHYLAMINO)PROPYL]PROPANE-1,3-DIAMINE TETRAHYDROCHLORIDE
- CBNumber
- CB51478063
- Molecular Formula
- C13H36Cl4N4
- Formula Weight
- 390.26374
- MOL File
- 156886-85-0.mol
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N,N''-BIS[3-(ETHYLAMINO)PROPYL]PROPANE-1,3-DIAMINE TETRAHYDROCHLORIDE Property
- storage temp.
- -10 to -25°C
- form
- Solid
- color
- White to off-white
- Water Solubility
- Soluble to 100 mM in water
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N-Bromosuccinimide Price
TRC
- Product number
- D367013
- Product name
- N1,N11-DiethylnorspermineTetrahydrochloride
- Packaging
- 5mg
- Price
- $305
- Updated
- 2021/12/16
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N,N''-BIS[3-(ETHYLAMINO)PROPYL]PROPANE-1,3-DIAMINE TETRAHYDROCHLORIDE Chemical Properties,Usage,Production
Uses
N1,N11-Diethylnorspermine Tetrahydrochloride is a polyamine analog binding to human serum albumin induce conformational transition and secondary structure change, a partial protein unfolding.
Biological Activity
DENSPM HCl is a nontoxic polyamine analog th at enhances polyamine catabolism and production of hazardous hydrogen peroxide and N-acetyl-3-aminopropanal by inducing spermidine/spermine-N1-acetyl transferase (SSAT) expression. DENSPM HCl improves stem cell maintenance through reduced translation, exhibits slower proliferation rates in cancer cells, and induces autophagy. It shows greater antitumor activity and less associated toxicity in a human melanoma xenograft model.
storage
Store at RT
N,N''-BIS[3-(ETHYLAMINO)PROPYL]PROPANE-1,3-DIAMINE TETRAHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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