(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester

Product Name: (2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester
CAS No.: 1142363-56-1
Chemical Name: (2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester
Synonyms: 4,4,5,5-tetramethyl-2-(2,2,6,6-tetramethyl-3H-pyran-4-yl)-1,3,2-dioxaborolane;2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-boronic Acid Pinacol Ester;2,2,6,6-TetraMethyl-3,6-dihydro-2H-pyran-4-boronic acid pinacol ester, 97%;(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester;2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-boronic acid pinacol ester, 97%,;(2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid pinacol ester;2,2,6,6-tetramethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyran;4,4,5,5-tetraMethyl-2-(2,2,6,6-tetraMethyl-3,6-dihydro-2H-pyran-4-yl)-1,3,2-dioxaborolane;2H-Pyran, 3,6-dihydro-2,2,6,6-tetramethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CBNumber: CB51486446
Molecular Formula: C15H27BO3
Formula Weight: 266.18
MOL File: 1142363-56-1.mol

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(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester Property

Boiling point:: 281.9±50.0 °C(Predicted)
Density: 0.97±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: solid
Appearance: White to off-white Solid
InChI: InChI=1S/C15H27BO3/c1-12(2)9-11(10-13(3,4)17-12)16-18-14(5,6)15(7,8)19-16/h9H,10H2,1-8H3
InChIKey: VOXXPMAJNSVUKJ-UHFFFAOYSA-N
SMILES: C1(C)(C)OC(C)(C)C=C(B2OC(C)(C)C(C)(C)O2)C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BML00218
Product name: (2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid pinacol ester
Purity: Aldrich
Packaging: 1g
Price: $569
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: BOR0001844
Product name: (2,2,6,6-TETRAMETHYL-3,6-DIHYDRO-2H-PYRAN-4-YL)BORONIC ACID, PINACOL ESTER
Purity: 95.00%
Packaging: 1G
Price: $509.01
Updated: 2021/12/16

AK Scientific

Product number: X3653
Product name: (2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid pinacol ester
Packaging: 250mg
Price: $167
Updated: 2021/12/16

Crysdot

Product number: CD11347231
Product name: 4,4,5,5-Tetramethyl-2-(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)-1,3,2-dioxaborolane
Purity: 95+%
Packaging: 1g
Price: $218
Updated: 2021/12/16

Chemenu

Product number: CM205111
Product name: 4,4,5,5-Tetramethyl-2-(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)-1,3,2-dioxaborolane
Purity: 95+%
Packaging: 1g
Price: $238
Updated: 2021/12/16

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(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester Chemical Properties,Usage,Production

Synthesis

1142363-55-0

73183-34-3

1142363-56-1

(b) 2,2,6,6-tetramethyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyran-1-yl 1,2,2,3,3,4,4,4-ninafluorobutane-1-sulfonate (43.8 g, 0.100 mol) was dissolved in anhydrous dimethoxyethane (DME, 500 mL ), bis(pinacolato)diboron (27.9 g, 0.109 mol), 1,1'-bis(diphenylphosphino)ferrocene (1.60 g, 2.90 mmol), and potassium acetate (KOAc, 29.4 g, 0.30 mol) were added sequentially. After degassing by sonication under argon protection, a 1:1 complex of [1,1'-bis(diphenylphosphino)-ferrocene]-palladium(II) dichloride with dichloromethane (2.19 g, 2.68 mmol) was added. The reaction mixture was heated and stirred at 80 °C overnight. After completion of the reaction, it was cooled to room temperature and filtered through a diatomaceous earth pad. The filtrate was concentrated under reduced pressure and the resulting residue was purified by silica gel column chromatography (eluent: 0-2% ethyl acetate/hexane) to afford (2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid pinacol ester as a white solid (17 g, 64% yield).1H-NMR (CDCl3; 400 MHz): δ 6.40 (t, 1H, J = 1.8 Hz), 1.97 (d, 2H, J = 1.8 Hz), 1.21 (s, 12H), 1.18 (s, 6H), 1.13 (s, 6H).

References

[1] Patent: US2009/105296, 2009, A1. Location in patent: Page/Page column 44

(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester Preparation Products And Raw materials

Raw materials

Preparation Products

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(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester Suppliers

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1142363-56-1, (2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol esterRelated Search:

2-bromo-6-(2,2,6,6-tetramethyltetrahydro-pyran-4-yl)pyridin-3-ylamine 2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-amine 6-(2,2,6,6-tetramethyl-tetrahydro-pyran-4-yl)-pyridin-3-ylamine 4-cyano-N-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-2-carboxamide 2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate 5-nitro-2-(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)-pyridine 4-cyano-N-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-yl)- 1H-imidazole-2-carboxamide

(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester

4,4,5,5-tetraMethyl-2-(2,2,6,6-tetraMethyl-3,6-dihydro-2H-pyran-4-yl)-1,3,2-dioxaborolane

2,2,6,6-TetraMethyl-3,6-dihydro-2H-pyran-4-boronic acid pinacol ester, 97%

2,2,6,6-tetramethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyran

2H-Pyran, 3,6-dihydro-2,2,6,6-tetramethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

4,4,5,5-tetramethyl-2-(2,2,6,6-tetramethyl-3H-pyran-4-yl)-1,3,2-dioxaborolane

2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-boronic acid pinacol ester, 97%,

(2,2,6,6-Tetramethyl-3,6-dihydro-2<i>H</i>-pyran-4-yl)boronic acid pinacol ester

2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-boronic Acid Pinacol Ester

1142363-56-1

C15H27BO3