1,3-phenyldiboronic acid, bis(pinacol) ester

Product Name: 1,3-phenyldiboronic acid, bis(pinacol) ester
CAS No.: 196212-27-8
Chemical Name: 1,3-phenyldiboronic acid, bis(pinacol) ester
Synonyms: 1,3-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene;1,3-Phenyldiboronic acid;M7122;JACS-196212-27-8;1,3-Benzenediborate dipinacol ester;1,3-Phenyldiboronic acid, pinacol ester;1,3-Phenylenediboronic Acid Pinacol Ester;4,4,5,5-Tetramethyl-2-[3-(tetramethyl-1,3;1,3-phenyldiboronic acid, bis(picol) ester;Benzene-1,3-diboronic acid, pinacol diester
CBNumber: CB51486451
Molecular Formula: C18H28B2O4
Formula Weight: 330.03
MOL File: 196212-27-8.mol

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1,3-phenyldiboronic acid, bis(pinacol) ester Property

Melting point:: 133.0 to 137.0 °C
Boiling point:: 430.9±28.0 °C(Predicted)
Density: 1.03±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: soluble in Methanol
form: powder to crystaline
color: White to Almost white
InChI: InChI=1S/C18H28B2O4/c1-15(2)16(3,4)22-19(21-15)13-10-9-11-14(12-13)20-23-17(5,6)18(7,8)24-20/h9-12H,1-8H3
InChIKey: LLQQCDJVSYEQQQ-UHFFFAOYSA-N
SMILES: C1(B2OC(C)(C)C(C)(C)O2)=CC=CC(B2OC(C)(C)C(C)(C)O2)=C1

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Safety

HS Code: 2931900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BML00188
Product name: 1,3-phenyldiboronic acid, bis(pinacol) ester
Purity: AldrichCPR
Packaging: 1g
Price: $179
Updated: 2025/07/31

TCI Chemical

Product number: B5070
Product name: 1,3-Benzenediboronic Acid Bis(pinacol) Ester
Purity: >98.0%(GC)
Packaging: 1g
Price: $117
Updated: 2025/07/31

TCI Chemical

Product number: B5070
Product name: 1,3-Benzenediboronic Acid Bis(pinacol) Ester
Purity: >98.0%(GC)
Packaging: 5g
Price: $349
Updated: 2025/07/31

TRC

Product number: T302798
Product name: 1,3-bis(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene
Packaging: 500mg
Price: $130
Updated: 2021/12/16

TRC

Product number: T302798
Product name: 1,3-bis(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene
Packaging: 50mg
Price: $45
Updated: 2021/12/16

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1,3-phenyldiboronic acid, bis(pinacol) ester Chemical Properties,Usage,Production

Synthesis

108-36-1

73183-34-3

196212-27-8

1. 1,3-dibromobenzene (2.5 g, 10.6 mmol), bis(pinacolato)diboron (6.0 g, 23.5 mmol), Pd(dppf)2Cl2 (0.9 g, 1.2 mmol), and potassium acetate (7.1 g, 72.1 mmol) were added into a reaction flask under the protection of argon. 2. The reaction mixture was degassed with argon for three times, then heated to 85 °C under argon atmosphere and reacted for 18 h. 3. After completion of reaction, it was cooled to room temperature and filtered. 4. The filtrate was extracted with ethyl acetate and the organic phases were combined. 5. The reaction mixture was then heated to 85 °C under argon atmosphere for 18 h. 3. After completion of the reaction, the reaction mixture was cooled to room temperature and filtered. 4. The filtrate was extracted with ethyl acetate and the organic phases were combined. 5. The organic phases were washed with water and saturated saline in turn. 6. The washed organic phases were dried with anhydrous sodium sulfate, filtered, and concentrated. 7. The resultant residue was purified by column chromatography on silica gel using an eluent of 1:9 ethyl acetate/hexanes mixture. 8. The eluent was a 1:9 solvent mixture of ethyl acetate/hexane. 8. The target fraction was collected and concentrated to remove the solvent. 9. The product was recrystallized from a solvent mixture of dichloromethane/methanol to give pinacol ester of 1,3-bis(phenylene diboron) acid as an off-white solid (3.008 g, 86% yield). 10.

References

[1] New Journal of Chemistry, 2018, vol. 42, # 6, p. 4728 - 4734
[2] Patent: US2012/226046, 2012, A1. Location in patent: Page/Page column 18; 19
[3] Organic Letters, 2007, vol. 9, # 4, p. 559 - 562
[4] Angewandte Chemie - International Edition, 2016, vol. 55, # 37, p. 11247 - 11250
[5] Angew. Chem., 2016, vol. 128, # 37, p. 11413 - 11417,5

1,3-phenyldiboronic acid, bis(pinacol) ester Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-phenyldiboronic acid, bis(pinacol) ester Suppliers

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View Lastest Price from 1,3-phenyldiboronic acid, bis(pinacol) ester manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 1,3-Phenyldiboronic acid, bis(pinacol) ester 196212-27-8
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-07-04

Hebei Xinsheng New Material Technology Co., LTD.

Product: 1,3-phenyldiboronic acid, bis(pinacol) ester 196212-27-8
Price: US $35.00-25.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 Ton
Release date: 2023-10-27

Hebei Xinsheng New Material Technology Co., LTD.

Product: 1,3-phenyldiboronic acid, bis(pinacol) ester 196212-27-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 30000 Kg
Release date: 2023-11-27

196212-27-8, 1,3-phenyldiboronic acid, bis(pinacol) esterRelated Search:

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1,3-Benzenediboronic Acid Bis(pinacol) Ester(contains varying amounts of Anhydride)

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196212-27-8

C18H32B2O6