(2-OXOPYRROLIDIN-1-YL)ACETIC ACID
- Product Name
- (2-OXOPYRROLIDIN-1-YL)ACETIC ACID
- CAS No.
- 53934-76-2
- Chemical Name
- (2-OXOPYRROLIDIN-1-YL)ACETIC ACID
- Synonyms
- Piracetam EP Impurity D;Piracetam Impuirty D;Piracetam Impurity 1;Piracetam Impurity D;(2-Oxopyrrolidin-1-yl)acetic;2-Pyrrolidinon-1-ylacetic acid;2-Oxopyrrolidine-1-acetic Acid;2-(2-oxopyrrolidin-1-yl)acetate;1-Pyrrolidineacetic acid, 2-oxo-;2-(2-oxo-1-pyrrolidinyl)acetic acid
- CBNumber
- CB51489588
- Molecular Formula
- C6H9NO3
- Formula Weight
- 143.14
- MOL File
- 53934-76-2.mol
(2-OXOPYRROLIDIN-1-YL)ACETIC ACID Property
- Melting point:
- 143℃ (benzene )
- Boiling point:
- 379.1±25.0 °C(Predicted)
- Density
- 1.319±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Sparingly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly)
- pka
- 3.75±0.10(Predicted)
- form
- Solid
- Appearance
- Off-white to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- O859610
- Product name
- (2-Oxopyrrolidin-1-yl)aceticAcid
- Packaging
- 1g
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 008404
- Product name
- (2-Oxo-pyrrolidin-1-yl)-acetic acid
- Packaging
- 500mg
- Price
- $30
- Updated
- 2021/12/16
- Product number
- W6820
- Product name
- 2-Oxo-1-pyrrolidineaceticacid
- Packaging
- 250mg
- Price
- $32
- Updated
- 2021/12/16
- Product number
- API0006090
- Product name
- 2-OXO-1-PYRROLIDINE ACETIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $188.1
- Updated
- 2021/12/16
- Product number
- API0006090
- Product name
- 2-OXO-1-PYRROLIDINE ACETIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $750.68
- Updated
- 2021/12/16
(2-OXOPYRROLIDIN-1-YL)ACETIC ACID Chemical Properties,Usage,Production
Uses
(2-Oxopyrrolidin-1-yl)acetic acid is a reagent in the preparation of pyrazolopyridines as PDE4B inhibitors.
Synthesis
143023-95-4
53934-76-2
Benzyl (2-oxopyrrolidin-1-yl) acetate (233 mg, 1.0 mmol) was dissolved in methanol (5 mL) at 23 °C and 10 wt% Pd/C catalyst (100 mg) was added. The reaction mixture was deoxygenated using a vacuum pump and subsequently reacted under hydrogen atmosphere (using a hydrogen balloon).After 3 h, the reaction mixture was filtered through a diatomaceous earth pad and the diatomaceous earth pad was washed with methanol (100 mL). The combined filtrates were concentrated under reduced pressure to afford (2-oxopyrrolidin-1-yl)acetic acid (143 mg, 100% yield).
References
[1] Patent: US2006/211603, 2006, A1. Location in patent: Page/Page column 76
(2-OXOPYRROLIDIN-1-YL)ACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (2-OXOPYRROLIDIN-1-YL)ACETIC ACID manufacturers
- Product
- Piracetam EP Impurity D 53934-76-2
- Price
- US $0.00-0.00/mg
- Min. Order
- 5mg
- Purity
- 95%+
- Supply Ability
- 1000mg
- Release date
- 2025-01-21
- Product
- (2-OXOPYRROLIDIN-1-YL)ACETIC ACID 53934-76-2
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-01-02