1H-Imidazole-4-carboxylic acid, 5-nitro-, methyl ester
- Product Name
- 1H-Imidazole-4-carboxylic acid, 5-nitro-, methyl ester
- CAS No.
- 20271-20-9
- Chemical Name
- 1H-Imidazole-4-carboxylic acid, 5-nitro-, methyl ester
- Synonyms
- Nsc26494;Methyl 5-Nitroimidazole-4-carboxylate;Methyl 4-nitro-1H-imidazol-5-carboxylate;methyl 4-nitro-1H-imidazole-5-carboxylate;methyl 5-nitro-1H-imidazole-4-carboxylate;Methyl 4-nitro-1H-imidazole-5-carboxylate - [M40981];1H-Imidazole-4-carboxylic acid, 5-nitro-, methyl ester
- CBNumber
- CB51509200
- Molecular Formula
- C5H5N3O4
- Formula Weight
- 171.11
- MOL File
- 20271-20-9.mol
1H-Imidazole-4-carboxylic acid, 5-nitro-, methyl ester Property
- Melting point:
- 212-213 °C
- Boiling point:
- 409.7±25.0 °C(Predicted)
- Density
- 1.545±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 5.99±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933299090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M223385
- Product name
- Methyl5-Nitro-1H-imidazole-4-carboxylate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 4H54-1-H7
- Product name
- Methyl 5-nitroimidazole-4-carboxylate
- Packaging
- 1g
- Price
- $392
- Updated
- 2021/12/16
- Product number
- CHM0986591
- Product name
- 1H-IMIDAZOLE-4-CARBOXYLIC ACID, 5-NITRO-, METHYL ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.81
- Updated
- 2021/12/16
- Product number
- 7123AJ
- Product name
- Methyl5-nitro-1H-imidazole-4-carboxylate
- Packaging
- 5g
- Price
- $667
- Updated
- 2021/12/16
- Product number
- 4H54-1-H7
- Product name
- Methyl 5-nitroimidazole-4-carboxylate
- Packaging
- 5G
- Price
- $1008
- Updated
- 2021/12/16
1H-Imidazole-4-carboxylic acid, 5-nitro-, methyl ester Chemical Properties,Usage,Production
Synthesis
67-56-1
1072-84-0
20271-20-9
The general procedure for the synthesis of methyl 5-nitro-1H-imidazole-4-carboxylate from methanol and 1H-imidazole-4-carboxylic acid was as follows: 45.0 g (0.56 mol) of ammonium nitrate was added in small amounts in batches to 160 ml of concentrated sulfuric acid solution containing 20.0 g (0.18 mol) of 1H-imidazole-4-carboxylic acid at 100 °C. The reaction mixture was stirred continuously at this temperature for 48 hours. Upon completion of the reaction, the mixture was cooled to room temperature, followed by the slow addition of 60 ml of methanol and maintaining stirring. Next, the reaction solution was warmed to 60°C and stirring was continued for 24 hours. At the end of the reaction, the mixture was cooled and poured into ice water to obtain a fine white solid precipitate.
References
[1] Patent: US2015/344499, 2015, A1. Location in patent: Paragraph 1044; 1045; 1046
[2] Patent: WO2005/49613, 2005, A1. Location in patent: Page/Page column 44
1H-Imidazole-4-carboxylic acid, 5-nitro-, methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Imidazole-4-carboxylic acid, 5-nitro-, methyl ester Suppliers
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