ChemicalBook > CAS DataBase List > L-Azidohomoalanine hydrochloride

L-Azidohomoalanine hydrochloride

Product Name
L-Azidohomoalanine hydrochloride
CAS No.
942518-29-8
Chemical Name
L-Azidohomoalanine hydrochloride
Synonyms
H-Dab(N3).HCl;H-L-Aha-OH*HCl;L-Dab(N3)-OH·HCl;H-Dab(N3)-OH.HCl;L-Azidohomoalanine (AHA);H-L-Aha-OH hydrochloride;4-Azido-L-homoalanine HCl;L-Azidohomoalanine hydrochloride;4-Azido-L-homoalanine hydrochloride;L-Azidohomoalanine (AHA) (CCT-1066)
CBNumber
CB51510785
Molecular Formula
C4H9ClN4O2
Formula Weight
180.59
MOL File
942518-29-8.mol
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L-Azidohomoalanine hydrochloride Property

Melting point:
139°C
storage temp. 
-20°C
solubility 
Soluble in DMSO
form 
powder or crystals
color 
White to off-white
Appearance
white to light beige powder
Water Solubility 
Soluble to 100 mM in water
InChI
1S/C4H8N4O2.ClH/c5-3(4(9)10)1-2-7-8-6;/h3H,1-2,5H2,(H,9,10);1H/t3-;/m0./s1
InChIKey
MHHYJRIDKLZZEO-DFWYDOINSA-N
SMILES
[Cl-].[N+H3][C@@H](CCN=[N+]=[N-])C(=O)O
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Safety

WGK Germany 
WGK 3
HS Code 
2922498590
Storage Class
5.2 - Organic peroxides and self-reacting hazardous materials
Hazard Classifications
Self-react. C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H242Heating may cause a fire

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P234Keep only in original container.

P235Keep cool.

P240Ground/bond container and receiving equipment.

P370+P378In case of fire: Use … for extinction.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
900892
Product name
L-Azidohomoalanine hydrochloride
Packaging
100MG
Price
$274
Updated
2026/03/19
Tocris
Product number
6584
Product name
L-Azidohomoalaninehydrochloride
Packaging
10
Price
$95
Updated
2021/12/16
Usbiological
Product number
258485
Product name
4-Azido-L-homoalanine hydrochloride
Packaging
100mg
Price
$340
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA11238
Product name
4-Azido-L-homoalanine hydrochloride
Packaging
2g
Price
$430
Updated
2021/12/16
Activate Scientific
Product number
AS87272
Product name
(S)-2-Amino-4-azido-butanoic acid HCl
Purity
95+% ee
Packaging
1g
Price
$505
Updated
2021/12/16
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L-Azidohomoalanine hydrochloride Chemical Properties,Usage,Production

Description

L-Azidohomoalanine (AHA) is a noncanonical amino acid analog of methionine that contains an azide moiety. AHA-labeling is a fast, sensitive, non-toxic, and non-radioactive alternative to the traditional technique for detecting nascent protein synthesis.


AHA is the cell-permeable compound randomly incorporated into synthesizing protein instead of methionine during translation. The resulting azide-labeled full-length proteins can be detected via copper-catalyzed click reaction (with fluorescent or biotin-labeled alkynes) or copper-free click reaction (with cycloalkynes) and used for subsequent microscopic imaging or purification tasks.

Chemical Properties

White crystalline powder

Uses

L-Azidohomoalanine (AHA) is an amino acid analog of methionine that contains a very small modification, specifically an azido moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click ” reaction between an azide and an alkyne or cyclooctyne. For example the azido-modified protein can be detected with either fluorescent alkyne or biotin alkyne. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.

reaction suitability

reaction type: click chemistry

IC 50

Alkyl-Chain

storage

Store at -20°C

L-Azidohomoalanine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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L-Azidohomoalanine hydrochloride Suppliers

Beijing HwrkChemical Technology Co., Ltd
Tel
89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9416
Advantage
55
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16059
Advantage
64
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9858
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15781
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Aikon International Limited
Tel
025-58859352 15955137747
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
huyue@rhawn.cn
Country
China
ProdList
14948
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
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View Lastest Price from L-Azidohomoalanine hydrochloride manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
L-Azidohomoalanine hydrochloride 942518-29-8
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-05

942518-29-8, L-Azidohomoalanine hydrochlorideRelated Search:


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