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6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole

Product Name
6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole
CAS No.
1038408-36-4
Chemical Name
6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole
Synonyms
Abesili impurity 6;Abemaciclib Impurity 70;Abemaciclib Impurity N5;6-bromo-1-isopropyl-2-methyl-benzimidazole;6-Bromo-2-methyl-1-propan-2-ylbenzimidazole;6-Bromo-1-isopropyl-2-methyl-1H-benzimidazole;6-BroMo-1-isopropyl-2-Methyl-1H-benzoiMidazole;6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole;6-Bromo-2-methyl-1-(1-methylethyl)-1H-benzimidazole;1H-BenziMidazole, 6-broMo-2-Methyl-1-(1-Methylethyl)-
CBNumber
CB51512350
Molecular Formula
C11H13BrN2
Formula Weight
253.14
MOL File
1038408-36-4.mol
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6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole Property

Boiling point:
353.9±15.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
5.20±0.10(Predicted)
Appearance
Light brown to brown Oil
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0367678
Product name
6-BROMO-1-ISOPROPYL-2-METHYL-1H-BENZO[D]IMIDAZOLE
Purity
95.00%
Packaging
5MG
Price
$496.19
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
35366
Product name
6-Bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole
Purity
95+%
Packaging
1g
Price
$850
Updated
2021/12/16
AK Scientific
Product number
0910AA
Product name
6-Bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole
Packaging
5g
Price
$1396
Updated
2021/12/16
Chemenu
Product number
CM130352
Product name
6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole
Purity
97%
Packaging
5g
Price
$954
Updated
2021/12/16
Crysdot
Product number
CD11361561
Product name
6-Bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole
Purity
97%
Packaging
5g
Price
$1010
Updated
2021/12/16
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6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole Chemical Properties,Usage,Production

Uses

6-Bromo-2-methyl-1-(1-methylethyl)-1H-benzimidazole is used in preparation of Amino Pyrimidine compound for inhibiting protein Tyrosine kinase activity.

Synthesis

1038408-35-3

64-19-7

1038408-36-4

Part D: 5-Bromo-N1-isopropyl-1,2-benzenediamine (0.56 g, 2.45 mmol) was dissolved in glacial acetic acid (20 mL), heated to reflux and stirred for 2 hours. The completion of the reaction was confirmed by LC-MS analysis. The reaction mixture was concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography (eluent: 5% methanol/dichloromethane) to afford 6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole (Compound 227) as a red oil in a yield of 0.55 g (90%).1H NMR (400 MHz, DMSO-d6) δ 7.82 (d,1H), 7.44 (1H) 7.24 (dd, 1H), 4.75 (m, 1H), 2.54 (s, 3H), 1.51 (d, 6H).

References

[1] Patent: WO2008/82487, 2008, A2. Location in patent: Page/Page column 110

6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole Suppliers

China 46 India 1 United States 5 Global 52
Nanjing JinruiJiuAn Biotechnology Co., Ltd.
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025-58196018 800028039
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025-83453306
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sales@fartop.net
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China
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Shanghai Topbiochem Technology Co., Ltd
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021-58170097
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info@topbiochem.com
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China
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Shanghai potentpharm CO.,Ltd
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13524892556
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(86) 21 51969655， QQ： 263541193
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sales-cn@potentpharm.com
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China
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SynAsst Chemical.
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021-60343070
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021-35122006
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China
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ShangHai KenEn Chemical Technology Co., Ltd.
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13120367189
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021-50315529
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parabiochem
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sale@parabiochem.com
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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Hubei Yangxin Medical Technology Co., Ltd.
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15374522761
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QQ:2853117752
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3003392093@yongstandards.com
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China
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10000
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Jiangxi ruiya pharmaceutical co., LTD
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0795-7229183 19170706235
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hwp@ruiyapharm.com
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China
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Biokitchen
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021-021-021-31663258 13795219287
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021-31663258
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donghuanwen@126.com
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1038408-36-4, 6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazoleRelated Search:

Tiotropium bromide

  • 6-bromo-1-isopropyl-2-methyl-1H-benzo[d]imidazole
  • 1H-BenziMidazole, 6-broMo-2-Methyl-1-(1-Methylethyl)-
  • 6-BroMo-1-isopropyl-2-Methyl-1H-benzoiMidazole
  • 6-Bromo-1-isopropyl-2-methyl-1H-benzimidazole
  • 6-Bromo-2-methyl-1-(1-methylethyl)-1H-benzimidazole
  • 6-Bromo-2-methyl-1-propan-2-ylbenzimidazole
  • 6-bromo-1-isopropyl-2-methyl-benzimidazole
  • Abesili impurity 6
  • Abemaciclib Impurity N5
  • Abemaciclib Impurity 70
  • 1038408-36-4