ChemicalBook > CAS DataBase List > 6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE

6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE

Product Name
6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE
CAS No.
3286-55-3
Chemical Name
6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE
Synonyms
4-Amino-6-chloro-2-methoxypyrimidine;6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE;4-Pyrimidinamine, 6-chloro-2-methoxy-;6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE ISO 9001：2015 REACH
CBNumber
CB51519667
Molecular Formula
C5H6ClN3O
Formula Weight
159.57
MOL File
3286-55-3.mol
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6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE Property

Melting point:
128-129 °C(Solv: benzene (71-43-2))
Boiling point:
337.8±45.0 °C(Predicted)
Density 
1.398±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
solid
pka
1.70±0.10(Predicted)
color 
Pale yellow
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C597818
Product name
6-Chloro-2-methoxypyrimidin-4-amine
Packaging
10mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA154222
Product name
4-Amino-6-chloro-2-methoxypyrimidine
Packaging
100mg
Price
$56
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA154222
Product name
4-Amino-6-chloro-2-methoxypyrimidine
Packaging
250mg
Price
$112.5
Updated
2021/12/16
AK Scientific
Product number
W5459
Product name
4-Amino-6-chloro-2-methoxypyrimidine
Packaging
100mg
Price
$118
Updated
2021/12/16
Apolloscientific
Product number
OR965821
Product name
4-Amino-6-chloro-2-methoxypyrimidine
Purity
95%
Packaging
250mg
Price
$131
Updated
2021/12/16
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6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE Chemical Properties,Usage,Production

Synthesis

10132-07-7

124-41-4

3286-55-3

General procedure for the synthesis of 4-amino-6-chloro-2-methoxypyrimidine from 4-amino-2,6-dichloropyrimidine and sodium methanol: Sodium methanol (12 mL, 25% wt of methanol solution) was added to methanol (300 mL), followed by addition of 4-amino-2,6-dichloropyrimidine (5.00 g, 30.5 mmol) to the mixture. The reaction mixture was heated to reflux for 2 h. After completion of the reaction, the solution was evaporated to dryness. The residue was treated with deionized water (250 mL) and the precipitate formed was separated by filtration and dried under vacuum to afford the title product 4-amino-6-chloro-2-methoxypyrimidine as a white solid (3 g, 61% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 3.92 (3H, s), 5.21 (2H, br s), 6.14 (1H, s).

References

[1] Patent: WO2005/47279, 2005, A1. Location in patent: Page/Page column 34

6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
6-Chloro-4-amino-2-methoxypyrimidine 3286-55-3
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-13
Career Henan Chemical Co
Product
6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE 3286-55-3
Price
US $1.00/KG
Min. Order
1g
Purity
98%
Supply Ability
200kgs
Release date
2020-01-09

3286-55-3, 6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINERelated Search:

2-[[4-CHLORO-6-[[(S)-ALPHA-METHYLBENZYL]AMINO]PYRIMIDIN-2-YL]OXY]BENZOIC ACID, METHYL ESTER 2-[[4-CHLORO-6-(DIMETHYLAMINO)PYRIMIDIN-2-YL]OXY]BENZOIC ACID, METHYL ESTER 6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE 2-[[4-CHLORO-6-(METHYLAMINO)PYRIMIDIN-2-YL]OXY]BENZOIC ACID, METHYL ESTER

  • 6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE
  • 4-Amino-6-chloro-2-methoxypyrimidine
  • 4-Pyrimidinamine, 6-chloro-2-methoxy-
  • 6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE ISO 9001：2015 REACH
  • 3286-55-3
  • Heterocycle-Pyrimidine series