2,6-difluoro-4-methylbenzaldehyde
Uses- Product Name
- 2,6-difluoro-4-methylbenzaldehyde
- CAS No.
- 1201597-22-9
- Chemical Name
- 2,6-difluoro-4-methylbenzaldehyde
- Synonyms
- 2,6-difluoro-4-methylbenzaldehyde;Benzaldehyde, 2,6-difluoro-4-methyl-
- CBNumber
- CB51557539
- Molecular Formula
- C8H6F2O
- Formula Weight
- 156.13
- MOL File
- 1201597-22-9.mol
2,6-difluoro-4-methylbenzaldehyde Property
- Boiling point:
- 198.8±35.0 °C(Predicted)
- Density
- 1.241±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2913000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- D474353
- Product name
- 2,6-Difluoro-4-methylbenzaldehyde
- Packaging
- 50mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- PC201051
- Product name
- 2,6-Difluoro-4-methylbenzaldehyde
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $359
- Updated
- 2021/12/16
- Product number
- HCH0065732
- Product name
- 2,6-DIFLUORO-4-METHYLBENZALDEHYDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.85
- Updated
- 2021/12/16
- Product number
- 3489AA
- Product name
- 2,6-Difluoro-4-methylbenzaldehyde
- Packaging
- 1g
- Price
- $717
- Updated
- 2021/12/16
- Product number
- PC201051
- Product name
- 2,6-Difluoro-4-methylbenzaldehyde
- Purity
- 95+%
- Packaging
- 1g
- Price
- $894
- Updated
- 2021/12/16
2,6-difluoro-4-methylbenzaldehyde Chemical Properties,Usage,Production
Uses
2,6-Difluoro-4-methylbenzaldehyde is a useful research chemical.
Synthesis
117358-51-7
68-12-2
1201597-22-9
Step B: Synthesis of 2,6-difluoro-4-methylbenzaldehyde To a solution of 1,3-difluoro-5-methylbenzene (10.2 g, 80 mmol) in anhydrous ether (80 mL), n-butyllithium (2.5 M hexane solution, 48 mL, 120 mmol) was slowly added at -50 °C, and the addition time was controlled to be within 20 minutes. The reaction temperature was maintained at -50 °C and stirring was continued for 1.5 hours. Subsequently, N,N-dimethylformamide (14.6 g, 200 mmol) was added dropwise over 20 min at the same temperature. After the dropwise addition, the temperature was kept constant and stirring was continued for 1.5 hours. After completion of the reaction, the reaction mixture was slowly poured into 1N aqueous sulfuric acid solution (300 mL) and extracted with ether three times. The organic layers were combined, washed with saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford the target product 2,6-difluoro-4-methylbenzaldehyde (11.2 g, 90% yield). 1H-NMR (500 MHz, CDCl3): δ 10.25 (s, 1H), 6.75 (d, 2H, J = 9.9Hz), 2.39 (s, 3H).
References
[1] Patent: WO2010/129208, 2010, A1. Location in patent: Page/Page column 32
[2] Patent: WO2009/152072, 2009, A1. Location in patent: Page/Page column 34-35
[3] Journal of the American Chemical Society, 2018, vol. 140, # 9, p. 3371 - 3377
[4] Patent: WO2011/32277, 2011, A1. Location in patent: Page/Page column 87
2,6-difluoro-4-methylbenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,6-difluoro-4-methylbenzaldehyde manufacturers
- Product
- 2,6-difluoro-4-methylbenzaldehyde 1201597-22-9
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 95%min
- Supply Ability
- 20kg/month
- Release date
- 2019-12-10