(S)-3-Amino-1,2,3,4-tetrahydrocarbazole
- Product Name
- (S)-3-Amino-1,2,3,4-tetrahydrocarbazole
- CAS No.
- 116650-34-1
- Chemical Name
- (S)-3-Amino-1,2,3,4-tetrahydrocarbazole
- Synonyms
- (S)-3-amino-1,2,3,4-terahydrocarbazole;(3S)-3-aMino-1,2,3,4-terahydrocarbazole;(S)-3-Amino-1,2,3,4-tetrahydrocarbazole;(3S)-3-Amino-1,2,3,4-tetrahydrocarbazole;(3S)-3-AaMino-1,2,3,4-terahydrocarbazole;(S)-2,3,4,9-tetrahydro-1H-carbazol-3-amine;(3S)-2,3,4,9-tetrahydro-1H-carbazol-3-amine;1H-Carbazol-3-amine, 2,3,4,9-tetrahydro-, (3S)-
- CBNumber
- CB51561929
- Molecular Formula
- C12H14N2
- Formula Weight
- 186.25
- MOL File
- 116650-34-1.mol
(S)-3-Amino-1,2,3,4-tetrahydrocarbazole Property
- Boiling point:
- 362.5±42.0 °C(Predicted)
- Density
- 1.191±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 17.54±0.40(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FA152035
- Product name
- (S)-3-Amino-1,2,3,4-tetrahydrocarbazole
- Packaging
- 2mg
- Price
- $59
- Updated
- 2021/12/16
- Product number
- FA152035
- Product name
- (S)-3-Amino-1,2,3,4-tetrahydrocarbazole
- Packaging
- 5mg
- Price
- $117
- Updated
- 2021/12/16
- Product number
- Z3476
- Product name
- (3S)-3-Amino-1,2,3,4-tetrahydrocarbazole
- Packaging
- 100mg
- Price
- $139
- Updated
- 2021/12/16
- Product number
- Z3476
- Product name
- (3S)-3-Amino-1,2,3,4-tetrahydrocarbazole
- Packaging
- 250mg
- Price
- $192
- Updated
- 2021/12/16
- Product number
- FA152035
- Product name
- (S)-3-Amino-1,2,3,4-tetrahydrocarbazole
- Packaging
- 10mg
- Price
- $203
- Updated
- 2021/12/16
(S)-3-Amino-1,2,3,4-tetrahydrocarbazole Chemical Properties,Usage,Production
Synthesis
97096-16-7
100-63-0
61894-99-3
General procedure for the synthesis of (S)-2,3,4,9-tetrahydro-1H-carbazol-3-amine from 8-amino-1,4-dioxaspiro[4,5]decane and phenylhydrazine: aqueous sulfuric acid (10% w/v, 30 mL) was added to a round-bottomed flask, followed by the addition of (1,4-dioxaspiro[4.5]dec-8-yl)dimethylamine (12a, 1.5 g, 8.1 mmol ). Phenylhydrazine (1.52 g, 14.08 mmol) was slowly added to the reaction mixture at room temperature. The reaction system was heated to reflux temperature (95-100°C) and maintained at reflux for 2-3 hours. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was cooled to 10-15°C. Subsequently, the pH was adjusted to alkaline with aqueous sodium hydroxide (20% w/v) and the aqueous phase was extracted with ethyl acetate. The organic layer was washed with saturated brine and dried with anhydrous sodium sulfate. The organic solvent was removed by distillation under reduced pressure to give the crude product. The crude product was purified by fast column chromatography (eluent: ethyl acetate/triethylamine = 9:0.2) to give (S)-2,3,4,9-tetrahydro-1H-carbazol-3-amine (13a, 0.8 g) in 50% yield.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 22, p. 6980 - 6985,6
(S)-3-Amino-1,2,3,4-tetrahydrocarbazole Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-3-Amino-1,2,3,4-tetrahydrocarbazole Suppliers
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View Lastest Price from (S)-3-Amino-1,2,3,4-tetrahydrocarbazole manufacturers
- Product
- (S)-3-Amino-1,2,3,4-tetrahydrocarbazole 116650-34-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-20
- Product
- (S)-3-Amino-1,2,3,4-tetrahydrocarbazole 116650-34-1
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11