4-BROMOTHIENO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
- Product Name
- 4-BROMOTHIENO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 145325-40-2
- Chemical Name
- 4-BROMOTHIENO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- Methyl 4-broMothieno[2,3-...;Methyl 4-bromothieno[2,3-c]pyridine-2-carboxyla;METHYL 4-BROMOTHIENO[2,3-C]PYRIDINE-2-CARBOXYLATE;4-BROMOTHIENO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER;Thieno[2,3-c]pyridine-2-carboxylic acid, 4-broMo-, Methyl ester
- CBNumber
- CB5158924
- Molecular Formula
- C9H6BrNO2S
- Formula Weight
- 272.12
- MOL File
- 145325-40-2.mol
4-BROMOTHIENO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Property
- Boiling point:
- 372.7±37.0 °C(Predicted)
- Density
- 1.697±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 1.21±0.40(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- M294493
- Product name
- Methyl4-bromothieno[2,3-c]pyridine-2-carboxylate
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- CS-0041247
- Product name
- Methyl4-bromothieno[2,3-c]pyridine-2-carboxylate
- Packaging
- 100mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- CS-0041247
- Product name
- Methyl4-bromothieno[2,3-c]pyridine-2-carboxylate
- Packaging
- 250mg
- Price
- $93
- Updated
- 2021/12/16
- Product number
- CS-0041247
- Product name
- Methyl4-bromothieno[2,3-c]pyridine-2-carboxylate
- Packaging
- 1g
- Price
- $166
- Updated
- 2021/12/16
- Product number
- 8H66-9-12
- Product name
- Methyl 4-bromothieno[2,3-c]pyridine-2-carboxylate
- Packaging
- 250mg
- Price
- $225
- Updated
- 2021/12/16
4-BROMOTHIENO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
70201-42-2
2365-48-2
145325-40-2
Under nitrogen atmosphere, 3,5-dibromopyridine-4-carboxaldehyde (80 g, 303 mmol) and cesium carbonate (98 g, 302 mmol) were sequentially added to a 2L round-bottomed flask containing tetrahydrofuran (1.3 L). Methyl mercaptoacetate (32 g, 302 mmol) was then added and the reaction mixture was stirred at 60 °C overnight. After completion of the reaction, it was cooled to room temperature and extracted by adding ethyl acetate. The organic layer was washed sequentially with water, saturated aqueous sodium bicarbonate solution and brine, dried over anhydrous sodium sulfate and filtered to give a white solid crude product. The crude product was purified by recrystallization from ethyl acetate to finally obtain methyl 4-bromothieno[2,3-C]pyridine-2-carboxylate (60 g, 73% yield).
References
[1] Patent: WO2013/127266, 2013, A1. Location in patent: Page/Page column 135
[2] Patent: WO2013/127267, 2013, A1. Location in patent: Page/Page column 86; 87
[3] Patent: WO2013/127268, 2013, A1. Location in patent: Page/Page column 64; 65
[4] Patent: WO2013/130935, 2013, A1. Location in patent: Paragraph 0188
[5] Journal of Heterocyclic Chemistry, 2008, vol. 45, # 1, p. 91 - 96
4-BROMOTHIENO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BROMOTHIENO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER manufacturers
- Product
- 4-BROMOTHIENO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 145325-40-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-99%
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-07