8-ISO PROSTAGLANDIN F2BETA

Product Name: 8-ISO PROSTAGLANDIN F2BETA
CAS No.: 177020-26-7
Chemical Name: 8-ISO PROSTAGLANDIN F2BETA
Synonyms: 8-ISO-9BETA-PGF2ALPHA;8-iso Prostaglandin F2β;8-ISO PROSTAGLANDIN F2BETA;PXGPLTODNUVGFL-HMALSPAFSA-N;8-isoprostaglandin PGF2beta;9alpha,11alpha,15S-trihydroxy-(8beta)-prost-5Z,13E-dien-1-oic-acid;9BETA,11ALPHA,15S-TRIHYDROXY-(8BETA)-PROSTA-5Z,13E-DIEN-1-OIC ACID;Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,8β,9β,11α,13E,15S)-;(Z)-7-[(1S,2R,3R,5R)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid
CBNumber: CB5162516
Molecular Formula: C20H34O5
Formula Weight: 354.48
MOL File: 177020-26-7.mol

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8-ISO PROSTAGLANDIN F2BETA Property

Boiling point:: 531.0±50.0 °C(Predicted)
Density: 1.153±0.06 g/cm3(Predicted)
solubility: 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
pka: 4.76±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16370
Product name: 8-iso Prostaglandin F2β
Purity: ≥98%
Packaging: 1mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 16370
Product name: 8-iso Prostaglandin F2β
Purity: ≥98%
Packaging: 5mg
Price: $324
Updated: 2024/03/01

Cayman Chemical

Product number: 16370
Product name: 8-iso Prostaglandin F2β
Purity: ≥98%
Packaging: 10mg
Price: $575
Updated: 2024/03/01

AK Scientific

Product number: 1518AH
Product name: 8-IsoprostaglandinF2beta
Packaging: 10mg
Price: $737
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0004711
Product name: 9ALPHA,11ALPHA,15S-TRIHYDROXY-(8BETA)-PROST-5Z,13E-DIEN-1-OIC-ACID
Purity: 99.00%
Packaging: 5MG
Price: $1621.4
Updated: 2021/12/16

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8-ISO PROSTAGLANDIN F2BETA Chemical Properties,Usage,Production

Description

8-iso Prostaglandin F_2β (8-iso PGF_2β) is an isomer of PGF_2α with a non-enzymatic, non-cyclooxygenase origin. It is one of 64 possible isomers of PGF_2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF_2β exhibits very weak contraction of human umbilical vein artery and does not promote aggregation of human whole blood. However, 8-iso PGF_2β moderately contracts both the canine and porcine pulmonary vein, although the effect is much weaker than that exhibited by other isoprostanes such as 8-iso PGE₁, 8-iso PGE₂, or 8-iso PGF_2α

Uses

8-iso Prostaglandin F2β (8-iso PGF2β) is a biomarker for assessing oxidative stress, and its content in serum can indirectly reflect the level of oxidative stress[1].

References

[1] Shaker S R, Al-Amran F, Fatima G, et al. Trimetazidine improves the outcome of EECP therapy in patients with refractory angina pectoris[J]. Medical Archives, 2020, 74(3): 199.

8-ISO PROSTAGLANDIN F2BETA Preparation Products And Raw materials

Raw materials

Preparation Products

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8-ISO PROSTAGLANDIN F2BETA Suppliers

CHINA 11 Switzerland 1 United Kingdom 1 United States 3 Global 16

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Cayman Chemical Company

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177020-26-7, 8-ISO PROSTAGLANDIN F2BETARelated Search:

8-EPI PGF2ALPHA-D4 8-EPI PROSTAGLANDIN F2ALPHA-D4 9ALPHA,11ALPHA,15S-TRIHYDROXY-(8BETA)-PROSTA-5Z,13E-DIEN-1-OIC-9-3H ACID 8-ISO PROSTAGLANDIN F2BETA

8-ISO-9BETA-PGF2ALPHA

8-ISO PROSTAGLANDIN F2BETA

9BETA,11ALPHA,15S-TRIHYDROXY-(8BETA)-PROSTA-5Z,13E-DIEN-1-OIC ACID

9alpha,11alpha,15S-trihydroxy-(8beta)-prost-5Z,13E-dien-1-oic-acid

(Z)-7-[(1S,2R,3R,5R)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid

8-isoprostaglandin PGF2beta

PXGPLTODNUVGFL-HMALSPAFSA-N

8-iso Prostaglandin F2β

Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,8β,9β,11α,13E,15S)-

177020-26-7