CARUMONAM
- Product Name
- CARUMONAM
- CAS No.
- 87638-04-8
- Chemical Name
- CARUMONAM
- Synonyms
- AMA 1080;CARUMONAM;Ro 17-2301;CarlliIIonaln;CARUMONAM USP/EP/BP;Ro-17-2301:A-masulin;Antibiotic Ro 17-2301;(2S)-2α-(Carbamoyloxymethyl)-3α-[[(Z)-(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-4-oxoazetidine-1-sulfonic acid;[[[(Z)-2-[[(2S)-2α-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3α-yl]amino]-1-(2-aminothiazol-4-yl)-2-oxoethylidene]amino]oxy]acetic acid;[[[(Z)-2-[[(2S,3S)-2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3-yl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
- CBNumber
- CB5165269
- Molecular Formula
- C12H14N6O10S2
- Formula Weight
- 466.4
- MOL File
- 87638-04-8.mol
CARUMONAM Property
- alpha
- D26 -45° (c = 1 in DMSO)
- Density
- 2.13±0.1 g/cm3(Predicted)
- pka
- -0.43±0.60(Predicted)
N-Bromosuccinimide Price
- Product number
- API0007950
- Product name
- CARUMONAM
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.38
- Updated
- 2021/12/16
- Product number
- MT-48971
- Product name
- Carumonam
- Purity
- 98%
- Packaging
- 0.1g
- Price
- $230
- Updated
- 2021/12/16
CARUMONAM Chemical Properties,Usage,Production
Description
Canunonam is an injectable antibiotic, the second monobactam ever developed (the first being Squibb’s aztreonam). It is highly active against Gram negative bacteria, particularly pseudomom, and is reportedly effective in the treatment of pneumonia, cystitis, peritonitis and secondary infections.
Originator
Takeda (Japan)
Definition
ChEBI: An N-sulfonated monobactam antibiotic.
brand name
Amasulin
Antimicrobial activity
A synthetic monobactam with activity against common
pathogenic organisms similar to that of aztreonam. It is resistant
to hydrolysis by the common plasmid and chromosomal
β-lactamases, but it can be hydrolyzed by ESBLs.
It is administered intravenously, achieving a concentration
of c. 78 mg/L after a 20-min infusion of 1 g. The plasma halflife
is 1.7 h and the plasma protein binding 18–28%.
Carumonam is almost entirely eliminated in the glomerular
filtrate, probenecid having no effect on excretion; 96%
of labeled compound is found in the urine, with 3% in the
feces. Between 68% and 91% of the dose appears in the urine
within 24 h.
Side effects and clinical use are similar to those of
aztreonam.
CARUMONAM Preparation Products And Raw materials
Raw materials
Preparation Products
CARUMONAM Suppliers
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View Lastest Price from CARUMONAM manufacturers
- Product
- CaruMonaM 87638-04-8
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-05-07
- Product
- CARUMONAM 87638-04-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2019-12-25