6-METHOXY-1,3-BENZOTHIAZOLE
- Product Name
- 6-METHOXY-1,3-BENZOTHIAZOLE
- CAS No.
- 2942-13-4
- Chemical Name
- 6-METHOXY-1,3-BENZOTHIAZOLE
- Synonyms
- NSC 508406;6-METHOXYBENZOTHIAZOLE;Benzothiazole,6-Methoxy-;6-Methoxybenzo[d]thiazole;6-METHOXY-1,3-BENZOTHIAZOLE;Benzothiazole, 6-methoxy- (7CI,8CI,9CI)
- CBNumber
- CB5188044
- Molecular Formula
- C8H7NOS
- Formula Weight
- 165.21
- MOL File
- 2942-13-4.mol
6-METHOXY-1,3-BENZOTHIAZOLE Property
- Melting point:
- 72.5-73℃
- Boiling point:
- 274.4±13.0 °C(Predicted)
- Density
- 1.268±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 1.60±0.10(Predicted)
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 29342000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M219355
- Product name
- 6-Methoxybenzothiazole
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 072317
- Product name
- 6-Methoxybenzothiazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $87
- Updated
- 2021/12/16
- Product number
- 072317
- Product name
- 6-Methoxybenzothiazole
- Purity
- 95+%
- Packaging
- 5g
- Price
- $255
- Updated
- 2021/12/16
- Product number
- W5194
- Product name
- 6-Methoxybenzothiazole
- Packaging
- 10g
- Price
- $303
- Updated
- 2021/12/16
- Product number
- 072317
- Product name
- 6-Methoxybenzothiazole
- Purity
- 95+%
- Packaging
- 10g
- Price
- $425
- Updated
- 2021/12/16
6-METHOXY-1,3-BENZOTHIAZOLE Chemical Properties,Usage,Production
Synthesis Reference(s)
Journal of Medicinal Chemistry, 16, p. 1314, 1973 DOI: 10.1021/jm00269a026
Synthesis
1747-60-0
2942-13-4
General procedure for the synthesis of 6-methoxybenzothiazole from 2-amino-6-methoxybenzothiazole: To a solution of tetrahydrofuran (THF, 100 mL) containing Example 18a (11.7 g, 0.065 mol) was added isoamyl nitrite (15.2 g, 0.13 mol) under nitrogen protection. The reaction mixture was stirred at 70 °C for 2 hours. Upon completion of the reaction, the reaction was quenched by the addition of water (500 mL), followed by extraction with ethyl acetate (EA, 500 mL x 2). The organic layers were combined, washed with brine (200 mL) and dried over anhydrous sodium sulfate (Na2SO4). After filtration, the filtrate was concentrated and purified by fast column chromatography to afford the target product 6-methoxybenzothiazole (Example 18b, 10.2 g, 95% yield) as a colorless oil.LCMS analysis showed [M + 1]+ = 166.
References
[1] Patent: WO2017/218960, 2017, A1. Location in patent: Paragraph 00453
[2] Chemical and Pharmaceutical Bulletin, 1997, vol. 45, # 9, p. 1547 - 1549
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 20, p. 5435 - 5438
[4] Tetrahedron, 1997, vol. 53, # 50, p. 17029 - 17038
[5] Organic and Biomolecular Chemistry, 2017, vol. 15, # 10, p. 2246 - 2252
6-METHOXY-1,3-BENZOTHIAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
6-METHOXY-1,3-BENZOTHIAZOLE Suppliers
- Tel
- --
- Fax
- --
- enquiries@fluorochem.co.uk
- Country
- United Kingdom
- ProdList
- 6401
- Advantage
- 74
View Lastest Price from 6-METHOXY-1,3-BENZOTHIAZOLE manufacturers
- Product
- 6-Methoxy-1,3-Benzothiazole 2942-13-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.6%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- 6-METHOXY-1,3-BENZOTHIAZOLE 2942-13-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-03