TRANS-2-BUTENAL DIETHYL ACETAL Property

Boiling point:

146-150 °C(lit.)

Density 

0.831 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.412(lit.)

Flash point:

93 °F

LogP

2.280 (est)

Safety

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

16-26-36/39

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

TRANS-2-BUTENAL DIETHYL ACETAL Chemical Properties,Usage,Production

Uses

trans-2-Butenal diethyl acetal may be used in the preparation of 2S,3S-epoxybutan-1-ol, an intermediate in the synthesis of erythromycin antibiotic.

General Description

trans-2-Butenal diethyl acetal is an acetal. Acetals are usually derived from the aldehydes. They have two single-bonded oxygen atoms attached to the same carbon atom. They are stable under basic conditions and they can be hydrolyzed back to the carbonyl compound. Acetals serves as a carbonyl protecting group and also are present as functional groups in glycosidic bonds. trans-2-Butenal diethyl acetal has been synthesized from trans-2-butenal with ethanol in the presence of methanesulfonic acid or methylsulfonate as catalysts.