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ChemicalBook > CAS DataBase List > 4-(3-BROMO-PHENYL)-THIAZOL-2-YLAMINE

4-(3-BROMO-PHENYL)-THIAZOL-2-YLAMINE

Application
Product Name
4-(3-BROMO-PHENYL)-THIAZOL-2-YLAMINE
CAS No.
105512-81-0
Chemical Name
4-(3-BROMO-PHENYL)-THIAZOL-2-YLAMINE
Synonyms
AURORA 22596;AKOS B000319;AKOS BBS-00008008;BUTTPARK 41\03-41;ART-CHEM-BB B000319;4-(3-bromophenyl)-2-thiazolamine;4-(3-BroMophenyl)thiazol-2-aMine;2-Amino-4-(3-bromophenyl)thiazole;2-Thiazolamine, 4-(3-bromophenyl)-;4-(3-Bromo-phenyl)-thiazol- 2-ylamin
CBNumber
CB5199983
Molecular Formula
C9H7BrN2S
Formula Weight
255.13
MOL File
105512-81-0.mol
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4-(3-BROMO-PHENYL)-THIAZOL-2-YLAMINE Property

Melting point:
130-131°C
Boiling point:
398.8±17.0 °C(Predicted)
Density 
1.636
storage temp. 
Storage temp. 2-8°C
pka
4.14±0.10(Predicted)
Appearance
White to yellow Solid
CAS DataBase Reference
105512-81-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
2934100090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B677928
Product name
4-(3-Bromophenyl)-1,3-thiazol-2-amine
Packaging
10mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
027785
Product name
4-(3-Bromophenyl)-1,3-thiazol-2-amine
Packaging
500mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB112294
Product name
4-(3-Bromophenyl)-1,3-thiazol-2-amine
Packaging
100mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
027785
Product name
4-(3-Bromophenyl)-1,3-thiazol-2-amine
Packaging
1g
Price
$76
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB112294
Product name
4-(3-Bromophenyl)-1,3-thiazol-2-amine
Packaging
250mg
Price
$100
Updated
2021/12/16
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4-(3-BROMO-PHENYL)-THIAZOL-2-YLAMINE Chemical Properties,Usage,Production

Application

2-Aminothiazole ring derivatives are an important group of heterocyclic compounds, and 2-amino-4-(3-bromophenyl)thiazole can be used as a pharmaceutical synthesis intermediate. This structure is widely used in the fields of pesticides and pharmaceuticals. Many natural products or small molecule drugs with anti-inflammatory, antitumor, antiviral, and sedative effects contain the 2-aminothiazole ring, making it one of the most frequently constructed functional groups in green drug research in recent years.

Synthesis

2-Amino-4-(3-bromophenyl)thiazole was prepared as follows: in a 25mL reaction vial, 3mL water, 30??L cyclodextrin, 0.50mmol1-bromo-3-ethylbenzene, 1.50mmolNBS and 0.05mmolAIBN were added sequentially and the reaction was carried out at 60??C for 4h. After the reaction was completed, it was cooled and then 1.50mmol sodium bicarbonate and 0.50mmol thiourea were added sequentially. mmol thiourea, and reacted at 80 ?? for 1h, at the end of the reaction, ethyl acetate was added, saturated saline was added to extract, the organic phase was concentrated, and column chromatography yielded 97 mg of white solid 2-amino-4-(3-bromophenyl)thiazole, the yield was 76%.

4-(3-BROMO-PHENYL)-THIAZOL-2-YLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(3-BROMO-PHENYL)-THIAZOL-2-YLAMINE Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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Bide Pharmatech Ltd.
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+86-21-61629029
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product02@bidepharm.com
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View Lastest Price from 4-(3-BROMO-PHENYL)-THIAZOL-2-YLAMINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-(3-Bromo-phenyl)-thiazol-2-ylamine 105512-81-0
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-06