2-Mercapto-4-methyl-5-thiazoleacetic acid
- Product Name
- 2-Mercapto-4-methyl-5-thiazoleacetic acid
- CAS No.
- 34272-64-5
- Chemical Name
- 2-Mercapto-4-methyl-5-thiazoleacetic acid
- Synonyms
- Etaa;MMTA;MTAA/MMTA;2-Mercapto-4-methyl-;Cefodizime Impurity A;Cefodizime Impurity 1;2-Mercapto-4-Methylthiazol;2-Mercapto-4-Methyl-5-Thiazole;Cefodizime 3-position side chain;（See C4X-12018）Cefodizime Impurity 1
- CBNumber
- CB5203286
- Molecular Formula
- C6H7NO2S2
- Formula Weight
- 189.26
- MOL File
- 34272-64-5.mol
2-Mercapto-4-methyl-5-thiazoleacetic acid Property
- Melting point:
- 207 °C (dec.) (lit.)
- Boiling point:
- 363.4±44.0 °C(Predicted)
- Density
- 1.52±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in DMSO, Methanol
- form
- powder to crystal
- pka
- 4.09±0.10(Predicted)
- color
- White to Light yellow
- λmax
- 320nm(H2O)(lit.)
- CAS DataBase Reference
- 34272-64-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 522317
- Product name
- 2-Mercapto-4-methyl-5-thiazoleacetic acid
- Purity
- 98%
- Packaging
- 10g
- Price
- $152.95
- Updated
- 2025/07/31
- Product number
- M2481
- Product name
- (2-Mercapto-4-methyl-5-thiazolyl)acetic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $30
- Updated
- 2025/07/31
- Product number
- M2481
- Product name
- (2-Mercapto-4-methyl-5-thiazolyl)acetic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $54
- Updated
- 2024/03/01
- Product number
- M254030
- Product name
- 2-Mercapto-4-methyl-5-thiazoleacetic acid
- Packaging
- 10g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- 126259
- Product name
- 2-(4-Methyl-2-thioxo-2,3-dihydrothiazol-5-yl)aceticacid
- Purity
- >95%
- Packaging
- 10g
- Price
- $126
- Updated
- 2021/12/16
2-Mercapto-4-methyl-5-thiazoleacetic acid Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powde
Uses
2-Mercapto-4-methyl-5-thiazoleacetic acid may be used as a capping agent in the preparation of fused spherical gold nanoparticles. It may also be used in the synthesis of eight-tin macrocyclic complex (a 40-membered macrocycle containing two distannoxane ladders).
General Description
2-Mercapto-4-methyl-5-thiazoleacetic acid is a thiazole derivative. It participates in the preparation of dinuclear [Au-(O4NCS2)]2 and tetranuclear [Au(SSCOOH)]4 complexes.
Synthesis
513-74-6
123-76-2
34272-64-5
To the reactor were added 100 kg of acetylpropionic acid and 1000 L of carbon tetrachloride. Under stirring conditions, 176 kg of sodium bromide was added, followed by a slow dropwise addition of 260 kg of hydrogen peroxide solution. The reaction mixture was heated to 60 °C and maintained at this temperature for 2.5 hours. Upon completion of the reaction, water was added for washing to separate the organic and aqueous phases. The aqueous phase was treated as waste water. To the organic phase, 75 kg of ammonium dithiocarbamate, 1000 kg of water and 22 kg of sodium carbonate were added directly to the organic phase to carry out the cyclization reaction. After completion of the reaction, the aqueous phase was acidified with acid at pH=1.5 to precipitate the product. Finally, 132 kg of 2-mercapto-4-methyl-5-thiazoleacetic acid was obtained with 99.92% purity and 80.99% yield.
References
[1] Patent: CN107602503, 2018, A. Location in patent: Paragraph 0024; 0025; 0026; 0027; 0028; 0029-0034
2-Mercapto-4-methyl-5-thiazoleacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Mercapto-4-methyl-5-thiazoleacetic acid manufacturers
- Product
- Cefodizime impurity 4 34272-64-5
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 95
- Supply Ability
- 100000
- Release date
- 2025-02-12
- Product
- 2-Mercapto-4-methyl-5-thiazoleacetic acid 34272-64-5
- Price
- US $199.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1 ton
- Release date
- 2021-12-21
- Product
- 2-Mercapto-4-methyl-5-thiazoleacetic acid 34272-64-5
- Price
- US $12.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2021-12-30