5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one

Product Name: 5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one
CAS No.: 678158-55-9
Chemical Name: 5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one
Synonyms: CLZ-8;Mcl1-IN-8;Mcl-1-Puma inhibitor 8;Mcl-1-IN-8,Mcl1IN8,Mcl1 IN 8;4(5H)-Thiazolone, 5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-;5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one
CBNumber: CB52056936
Molecular Formula: C22H23N3O2S
Formula Weight: 393.5
MOL File: 678158-55-9.mol

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5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one Property

Boiling point:: 596.6±60.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 50 mg/mL (127.06 mM)
pka: 14.96±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC20444
Product name: Mcl-1-Pumainhibitor8
Purity: >98%
Packaging: 100mg
Price: $700
Updated: 2021/12/16

DC Chemicals

Product number: DC20444
Product name: Mcl-1-Pumainhibitor8
Purity: >98%
Packaging: 250mg
Price: $1400
Updated: 2021/12/16

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5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one Chemical Properties,Usage,Production

Description

Mcl-1-PUMA modulator-8 is a modulator of Mcl-1-PUMA interaction which suppresses cancer cells and inhibits PUMA-dependent apoptosis of non-cancerous cells.

5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one Suppliers

China 7 Finland 1 The Netherlands 1 United States 2 Global 11

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9730
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
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Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24131
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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

Tel: 021-59167510 18117107507
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Nanjing Shizhou Biology Technology Co.,Ltd

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Fax: 025-85563444
Email: cindy.huang@synzest.com
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RD International Technology Co., Limited

Tel: 18988968278
Email: sales@ubiochem.com
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Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
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Advantage: 58

678158-55-9, 5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-oneRelated Search:

5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-thiazol-4(5H)-one

Mcl1-IN-8

Mcl-1-Puma inhibitor 8

Mcl-1-IN-8,Mcl1IN8,Mcl1 IN 8

4(5H)-Thiazolone, 5-([1,1'-biphenyl]-4-ylmethylene)-2-[4-(2-hydroxyethyl)-1-piperazinyl]-

CLZ-8

678158-55-9