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TAPI-1

Product Name
TAPI-1
CAS No.
163847-77-6
Chemical Name
TAPI-1
Synonyms
TAPI-1;(2R)-TAPI-1;TAPI-1 acetate salt;TNF-ALPHA PROTEASE INHIBITOR-1;HONHCOCH2CH(CH2-CH(CH3)2)CO-NAL-ALA-NHCH2CH2NH2;N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)--alanyl-L-alaninamide;N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE, 2-AMINOETHYL AMIDE;N-(R)-(2-(HYDROXYAMINOCARBONYL)METHYL)-4-METHYLPENTANOYL-L-3-(2'-NAPHTHYL)ALANYL-L-ALANINE 2-AMINOETHYL AMIDE;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-;N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-Alaninamide acetate salt
CBNumber
CB5206757
Molecular Formula
C26H37N5O5
Formula Weight
499.6
MOL File
Mol file
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TAPI-1 Property

Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka
9.17±0.20(Predicted)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HS Code 
2928009090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0739
Product name
TAPI-1 acetate salt
Purity
≥97% (HPLC)
Packaging
1mg
Price
$393
Updated
2024/03/01
Tocris
Product number
6162
Product name
TAPI1
Purity
≥95%(HPLC)
Packaging
1
Price
$288
Updated
2021/12/16
TRC
Product number
T731505
Product name
TAPI1
Packaging
1mg
Price
$270
Updated
2021/12/16
ChemScene
Product number
CS-3108
Product name
TAPI-1
Purity
≥99.0%
Packaging
1mg
Price
$216
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000228
Product name
TAPI-1
Purity
95.00%
Packaging
1MG
Price
$466.2
Updated
2021/12/16
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TAPI-1 Chemical Properties,Usage,Production

Uses

TAPI-1 acetate salt has been used as a tumor necrosis factor(TNF)-α convertase/ADAM17/α-secretase (TACE) inhibitor.

Biochem/physiol Actions

TAPI-1 is a potent inhibitor of matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase).

storage

Store at -20°C

TAPI-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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TAPI-1 Suppliers

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163847-77-6, TAPI-1Related Search:


  • HONHCOCH2CH(CH2-CH(CH3)2)CO-NAL-ALA-NHCH2CH2NH2
  • TAPI-1
  • N-(R)-(2-(HYDROXYAMINOCARBONYL)METHYL)-4-METHYLPENTANOYL-L-3-(2'-NAPHTHYL)ALANYL-L-ALANINE 2-AMINOETHYL AMIDE
  • N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)--alanyl-L-alaninamide
  • N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE, 2-AMINOETHYL AMIDE
  • TNF-ALPHA PROTEASE INHIBITOR-1
  • N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-Alaninamide acetate salt
  • TAPI-1 acetate salt
  • L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-
  • (2R)-TAPI-1
  • (R)-N1-((S)-1-(((S)-1-((2-Aminoethyl)amino)-1-oxopropan-2-yl)amino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide
  • 163847-77-6