ChemicalBook > CAS DataBase List > 4-Hydroxybenzylamine

4-Hydroxybenzylamine

Product Name
4-Hydroxybenzylamine
CAS No.
696-60-6
Chemical Name
4-Hydroxybenzylamine
Synonyms
4-(AMINOMETHYL)PHENOL;4-HOBA;AI320348;AI3 20348;AI3-20348;NSC 125720;RARECHEM AL BW 0048;4-HYDROXYBENZYLAMINE;Bisoprolol Impurity 26;Phenol, 4-(aminomethyl)-
CBNumber
CB5207547
Molecular Formula
C7H9NO
Formula Weight
123.15
MOL File
696-60-6.mol
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4-Hydroxybenzylamine Property

Melting point:
123-128 °C
Boiling point:
262.4±15.0 °C(Predicted)
Density 
1.141±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO (Slightly), Water (Slightly, Heated)
pka
8.93±0.26(Predicted)
form 
Powder
color 
Off-white to pale yellow
InChIKey
RQJDUEKERVZLLU-UHFFFAOYSA-N
LogP
0.350 (est)
CAS DataBase Reference
696-60-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
34-36/37/38
Safety Statements 
26-36/37/39-24/25
RIDADR 
2735
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
IRRITANT, CORROSIVE
HS Code 
29214990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
776505
Product name
4-Hydroxybenzylamine
Packaging
5g
Price
$69.2
Updated
2024/03/01
Sigma-Aldrich
Product number
776505
Product name
4-Hydroxybenzylamine
Packaging
25g
Price
$102
Updated
2024/03/01
TCI Chemical
Product number
A2305
Product name
4-(Aminomethyl)phenol
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
25398
Product name
4-HOBA
Packaging
10g
Price
$53
Updated
2024/03/01
Cayman Chemical
Product number
25398
Product name
4-HOBA
Packaging
25g
Price
$82
Updated
2024/03/01
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4-Hydroxybenzylamine Chemical Properties,Usage,Production

Description

4-HOBA is an isomer of the isoketal scavenger 2-HOBA that has reduced efficacy as an isoketal scavenger. Unlike 2-HOBA, 4-HOBA has no effect on hypertension induced by angiotensin II in mice. 4-HOBA has been used as a negative control for the activity of 2-HOBA and related compounds in a mouse model of hypertension.

Chemical Properties

4-Hydroxybenzylamine, also known as tyramine and p-hydroxyphenethylamine, is a white or off-white or light green solid. Tyramine, a compound originally isolated from ergot alkaloids and decomposed animal tissues, is an important synthetic drug intermediate.

Uses

4-Hydroxybenzylamine (cas# 696-60-6) is a compound useful in organic synthesis.

Preparation

Synthesis of 4-Hydroxybenzylamine:Ammonia is passed into 500 ml of ethanol at 10° C. until saturation is reached, 122.1 g=1 mole of p-hydroxybenzaldehyde, 20 g of Raney nickel and 0.1 ml of concentrated sulfuric acid are added and the mixture is stirred in an autoclave for 6 hours at room temperature and under a hydrogen pressure of 100 atmospheres. After releasing the pressure, the catalyst is filtered off and the filtrate is boiled up with active charcoal, filtered and concentrated. The residue is recrystallized from a mixture of ethanol and ether. This gives 104 g (85% of theory), melting point: 104° C.
Literature source US04391805

Definition

ChEBI: 4-Hydroxybenzylamine is an aromatic amine.

target

GABA Receptor

4-Hydroxybenzylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxybenzylamine Suppliers

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View Lastest Price from 4-Hydroxybenzylamine manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
4-Hydroxybenzylamine 696-60-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-09-29
Hebei Guanlang Biotechnology Co,.LTD
Product
4-Hydroxybenzylamine 696-60-6
Price
US $1.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2021-08-12
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Hydroxybenzylamine 696-60-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11

696-60-6, 4-HydroxybenzylamineRelated Search:

Itopride Impurity C Itopride Impurity A Itopride N-Oxide ETHYL 3,4-DIMETHOXYBENZOATE NA 4-[2-(DIMETHYLAMINO)ETHOXY]BENZYLAMINE 3,4-DIMETHOXYBENZOYL CHLORIDE Itopride Impurity 1 2-(p-tolyloxy)-N,N-dimethylethanamine hydrochloride Benzaldehyde, 4-[2-(diMethylaMino)ethoxy]-, oxiMe Benzoic acid, 3,4-dimethoxy-, 4-formylphenyl ester Itopride Impurity B DL-LAUDANOSINE 3,4-Dichlorobenzylamine Veratrylamine 4-Ethoxybenzamide 4-Methoxybenzamide 1-Benzylpiperazine

  • RARECHEM AL BW 0048
  • 4-HYDROXYBENZYLAMINE[4-(AMINOMETHYL)PHENOL]
  • 4-(AMINOMETHYL)PHENOL
  • 4-HYDROXYBENZYLAMINE
  • 4-Hydroxybenzylamine, (4-Hydroxyphenyl)methylamine
  • 4-(aminomethyl)phenol hydrochloride
  • 4-Hydroxybenzylamine monohydrate, 97%
  • [(4-Hydroxyphenyl)Methyl]aMine
  • 4-HydroxybenzeneMethanaMine
  • NSC 125720
  • p-HydroxybenzeneMethanaMine
  • 4-HydroxybenzylaMine hydrate, 97%
  • 4-Hydroxybenzylamine, 97.5%
  • 4-HOBA
  • 4-(Aminomethyl)phenol &gt
  • Phenol, 4-(aminomethyl)-
  • Bisoprolol Impurity 26
  • TIANFU-CHEM_Phenol,4-(aminomethyl)- 696-60-6
  • AI3 20348
  • AI320348
  • AI3-20348
  • 696-60-6
  • Amines
  • Aromatics
  • Intermediates
  • Anilines, Aromatic Amines and Nitro Compounds