S-adenosylmethionine

Product Name: S-adenosylmethionine
CAS No.: 485-80-3
Chemical Name: S-adenosylmethionine
Synonyms: 13CH3-SAM;Methionine,active;S-ADENOSYLMETHIONINE;Adenosine Impurity 39;S-(5'-Adenosyl)methionine;MEFKEPWMEQBLKI-AIRLBKTGSA-O;S-adenosylmethionine USP/EP/BP;Ademetionine 1,4-Butanedisulfonate Impurity 18 Monomer;Galactose Impurity 1 (Galactose EP Impurity A)(Lactose);S-Adenosyl-L-methionine sulfate p-toluene sulfonate salt
CBNumber: CB52131161
Molecular Formula: C15H23N6O5S
Formula Weight: 400.45
MOL File: 485-80-3.mol

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S-adenosylmethionine Property

InChIKey: QOWKLNSTGYYNGX-MDHPBGAINA-N
SMILES: C(O)(=O)[C@H](CCS(C[C@H]1O[C@@H](N2C3=C(C(=NC=N3)N)N=C2)[C@H](O)[C@@H]1O)C)N |&1:3,8,10,21,23,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological

Product number: 353212
Product name: S-adenosylmethionine
Packaging: 100Tests
Price: $1217
Updated: 2021/12/16

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S-adenosylmethionine Chemical Properties,Usage,Production

Uses

S-Adenosyl-methionine labelled-15N5 is a useful research chemical. CAS# 485-80-3 is used in ReFlexIn, flexible receptor protein-ligand docking scheme evaluated on HIV-1 protease.

Definition

ChEBI: S-adenosyl-L-methionine is a sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine. It has a role as a coenzyme, a nutraceutical, a micronutrient, a human metabolite, a Saccharomyces cerevisiae metabolite, a Mycoplasma genitalium metabolite and a cofactor. It is a conjugate acid of a S-adenosyl-L-methioninate. It is an enantiomer of a S-adenosyl-D-methionine. It is a tautomer of a S-adenosyl-L-methionine zwitterion.

Synthesis

S-adenosylmethionine is synthesized intracellularly from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase catalyzed by the loss of a methyl group to S-adenosylhomocysteine while participating in a methyl transfer reaction as a coenzyme. Most of the S-adenosyl methionine is produced in the liver.

Veterinary Drugs and Treatments

In small animal medicine, SAMe is most commonly used as an adjunctive treatment for liver disease (chronic hepatitis, hepatic lipidosis, cholangiohepatitis, feline triad disease, etc.). It may also be of benefit in osteoarthritis, treatment of acute hepatotoxin-induced liver toxicity (e.g., acetaminophen toxicity), and at-risk patients on long-term therapy using drugs with hepatotoxic potential.
In humans, SAMe is being used as a treatment for depression, osteoarthritis, AIDS-related myopathy, intrahepatic cholestasis, liver disease, alcoholic liver cirrhosis, fibromyalgia, adult ADHD, Alzheimer’s, migraines, etc.

S-adenosylmethionine Preparation Products And Raw materials

Raw materials

Preparation Products

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S-adenosylmethionine Suppliers

China 29 India 1 Global 30

GIHI CHEMICALS CO.,LTD

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View Lastest Price from S-adenosylmethionine manufacturers

Jinan Million Pharmaceutical Co., Ltd

Product: S-adenosylmethionine 485-80-3
Price: US $1.00/kg
Min. Order: 0.10000000kg
Purity: 99%
Supply Ability: 200kg
Release date: 2025-11-10

Hebei Zhanyao Biotechnology Co. Ltd

Product: S-adenosylmethionine 485-80-3
Price: US $10.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-11-23

485-80-3, S-adenosylmethionineRelated Search:

S-ADENOSYLMETHIONINE

5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine

5'-Adenosyl(methyl)(3-amino-4-oxo-4-hydroxybutyl)sulfonium

Methionine,active

S-(5'-Adenosyl)methionine

S-Adenosyl-L-methionine sulfate p-toluene sulfonate salt

MEFKEPWMEQBLKI-AIRLBKTGSA-O

13CH3-SAM

S-adenosylmethionine USP/EP/BP

Adenosine Impurity 39

Galactose Impurity 1 (Galactose EP Impurity A)(Lactose)

Ademetionine 1,4-Butanedisulfonate Impurity 18 Monomer

Adenosine, 5'-?[[(3S)?-?3-?amino-?3-?carboxypropyl]?methylsulfonio]?-?5'-?deoxy-

485-80-3