BREVETOXIN PBTX-3
- Product Name
- BREVETOXIN PBTX-3
- CAS No.
- 85079-48-7
- Chemical Name
- BREVETOXIN PBTX-3
- Synonyms
- PBTX-3;toxint-17;Gb 3 toxin;BREVETOXIN3;PUMILIOTOXIN;brevetoxint17;BREVETOXIN PBTX-3;DIHYDROBREVETOXIN B;BKMHDYJRAAJTAD-RXUQWMQDSA-N;42-Hydroxy-42-deoxobrevetoxin B
- CBNumber
- CB5221763
- Molecular Formula
- C50H72O14
- Formula Weight
- 897.1
- MOL File
- 85079-48-7.mol
BREVETOXIN PBTX-3 Property
- Density
- 1.190±0.06 g/cm3(Predicted)
- storage temp.
- -20C
- solubility
- DMSO: soluble,Ethanol: soluble,Methanol: soluble
- form
- Solid
- pka
- 13.78±0.70(Predicted)
- color
- White to off-white
Safety
- RIDADR
- 3172
- RTECS
- XW5885000
- HazardClass
- 6.1(a)
- PackingGroup
- I
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P391Collect spillage. Hazardous to the aquatic environment
P405Store locked up.
BREVETOXIN PBTX-3 Chemical Properties,Usage,Production
General Description
Lipid-soluble polyether marine toxin produced by the red tide dinoflagellate, Ptychodiscus brevis, found along the Gulf Coast of Florida. Voltage-dependent Na+ channel activator that causes contractile paralysis in animal models by binding to a unique site on these channels. The excitatory action of brevetoxins on nerve and muscle membranes is responsible for a wide spectrum of the toxic effects, including massive transmitter release from nerve endings, muscle fasciculations, and ventricular fibrillation. The toxin does not bind to either tetrodotoxin or aconitine/veratridine sites.
Biochem/physiol Actions
Primary TargetVoltage-dependent Na+ channel activator
Safety Profile
A poison by ingestion, intraperitoneal, and intravenous routes. When heated to decomposition it emits acrid smoke and irritating vapors.
BREVETOXIN PBTX-3 Preparation Products And Raw materials
Raw materials
Preparation Products
BREVETOXIN PBTX-3 Suppliers
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