ChemicalBook > CAS DataBase List > (R)-(+)-Ketorolac

(R)-(+)-Ketorolac

Product Name
(R)-(+)-Ketorolac
CAS No.
66635-93-6
Chemical Name
(R)-(+)-Ketorolac
Synonyms
(1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(+)-Ketorolac;(R)-Ketorolac;(R)-(+)-Ketorolac;Ketorolac R-IsoMer;(R)-Ketorolac [(+)-Ketorolac);(R)-(+)-Ketorolac ISO 9001：2015 REACH;Ketorolac impurity 1/Ketorolac R-Isomer;(R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(R)-Ketorolac,inhibit,Inhibitor,(R) Ketorolac,(R)Ketorolac
CBNumber
CB52226607
Molecular Formula
C15H13NO3
Formula Weight
255.27
MOL File
66635-93-6.mol
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(R)-(+)-Ketorolac Property

Melting point:
163-170°C
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
powder
color 
white to beige
optical activity
[α]/D +162 to +178°, c = 1 in methanol
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1654
Product name
R-Ketorolac
Purity
≥95% (HPLC)
Packaging
5MG
Price
$238
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1654
Product name
R-Ketorolac
Purity
≥95% (HPLC)
Packaging
25MG
Price
$953
Updated
2023/06/20
TRC
Product number
K235600
Product name
(R)-Ketorolac
Packaging
100mg
Price
$1620
Updated
2021/12/16
TRC
Product number
K235600
Product name
(R)-Ketorolac
Packaging
50mg
Price
$920
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010456
Product name
(+)-KETOROLAC
Purity
95.00%
Packaging
2MG
Price
$350
Updated
2021/12/16
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(R)-(+)-Ketorolac Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

(R)-Ketorolac is the R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.

Definition

ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has R configuration. Unlike the S-enantiomer, it does not exhibit COX1 and COX2 inhibition, but does exhibit analgesic activity. Racemic keto olac, known simply as ketorolac, is used (mainly as a tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.

Biochem/physiol Actions

R-Ketorolac is potent and selective Rho-family GTPases Cdc42 (cell division control protein 42) and Rac1 (Ras-related C3 botulinum toxin substrate 1) allosteric inhibitor that modulates downstream GTPase-dependent physiologic responses critical to tumor metastasis. R-ketorolac significantly inhibits ovarian cancer cell adhesion, migration, and invasion.

(R)-(+)-Ketorolac Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(+)-Ketorolac Suppliers

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View Lastest Price from (R)-(+)-Ketorolac manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
(R)-(+)-Ketorolac 66635-93-6
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-13
Dideu Industries Group Limited
Product
(R)-(+)-Ketorolac 66635-93-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-21

66635-93-6, (R)-(+)-KetorolacRelated Search:

(S)-Ketorolac Ketorolac Impurity 48 Ketorolac Impurity 43 Ketorolac Impurity 31 Ketorolac Impurity 24 (5-chloro-1H-pyrrol-2-yl)-phenylmethanone Ethyl 2-(1H-pyrrol-2-yl)acetate Ketorolac Related Compound A (20 mg) (5-benzoyl-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-2,3-dihydro-1H-pyrrolizine-1-carboxamide) Ethyl-(5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic Ketorolac Impurity 54 4-HYDROXY KETOROLAC Ketorolac tromethamine Ketorolac Impurity 21 KETOROLAC EP IMPURITY H Ketorolac EP IMpurity D 1-Descarboxy Ketorolac Ketorolac EP IMpurity G 2,2'-BIPYRROL

  • Ketorolac R-IsoMer
  • (1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
  • Ketorolac impurity 1/Ketorolac R-Isomer
  • (R)-(+)-Ketorolac
  • (R)-Ketorolac
  • 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1R)-
  • (R)-(+)-Ketorolac ISO 9001：2015 REACH
  • (R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
  • (R)-Ketorolac [(+)-Ketorolac)
  • (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acidQ: What is (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Q: What is the CAS Number of (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Q: What is the storage condition of (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
  • (+)-Ketorolac
  • (R)-Ketorolac,inhibit,Inhibitor,(R) Ketorolac,(R)Ketorolac
  • 66635-93-6
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  • Chiral Reagents
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  • Inhibitors
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