ChemicalBook > CAS DataBase List > (R)-(+)-Ketorolac

(R)-(+)-Ketorolac

Product Name
(R)-(+)-Ketorolac
CAS No.
66635-93-6
Chemical Name
(R)-(+)-Ketorolac
Synonyms
(1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(+)-Ketorolac;(R)-Ketorolac;(R)-(+)-Ketorolac;Ketorolac R-IsoMer;(R)-Ketorolac [(+)-Ketorolac);(R)-(+)-Ketorolac ISO 9001：2015 REACH;Ketorolac impurity 1/Ketorolac R-Isomer;(R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(R)-Ketorolac,inhibit,Inhibitor,(R) Ketorolac,(R)Ketorolac
CBNumber
CB52226607
Molecular Formula
C15H13NO3
Formula Weight
255.27
MOL File
66635-93-6.mol
More
Less

(R)-(+)-Ketorolac Property

Melting point:
163-170°C
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
powder
color 
white to beige
optical activity
[α]/D +162 to +178°, c = 1 in methanol
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1654
Product name
R-Ketorolac
Purity
≥95% (HPLC)
Packaging
5MG
Price
$238
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1654
Product name
R-Ketorolac
Purity
≥95% (HPLC)
Packaging
25MG
Price
$953
Updated
2023/06/20
TRC
Product number
K235600
Product name
(R)-Ketorolac
Packaging
100mg
Price
$1620
Updated
2021/12/16
TRC
Product number
K235600
Product name
(R)-Ketorolac
Packaging
50mg
Price
$920
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010456
Product name
(+)-KETOROLAC
Purity
95.00%
Packaging
2MG
Price
$350
Updated
2021/12/16
More
Less

(R)-(+)-Ketorolac Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

(R)-Ketorolac is the R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.

Definition

ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has R configuration. Unlike the S-enantiomer, it does not exhibit COX1 and COX2 inhibition, but does exhibit analgesic activity. Racemic keto olac, known simply as ketorolac, is used (mainly as a tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.

Biochem/physiol Actions

R-Ketorolac is potent and selective Rho-family GTPases Cdc42 (cell division control protein 42) and Rac1 (Ras-related C3 botulinum toxin substrate 1) allosteric inhibitor that modulates downstream GTPase-dependent physiologic responses critical to tumor metastasis. R-ketorolac significantly inhibits ovarian cancer cell adhesion, migration, and invasion.

(R)-(+)-Ketorolac Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-(+)-Ketorolac Suppliers

Canada 1 China 40 India 4 United States 6 Global 51
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7892
Advantage
55
Tonichem Pharmaceutical Technology Co., Ltd.
Tel
+86 (0752) 222-7171, +86 15815821171
Fax
+86 (0752) 222-6171
Country
China
ProdList
1120
Advantage
58
Shanghai CR Corporation Limited
Tel
021-80270511; 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
10044
Advantage
58
Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15951
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57423
Advantage
58
Shanghai Fuyi Biological Technology Co., Ltd.
Tel
18096642264
Email
sales@foreversyn.com
Country
China
ProdList
492
Advantage
58
CR Corporation Limited
Tel
+8613062833949
Email
fred.wen@crcorporation.cn
Country
China
ProdList
8647
Advantage
58
ANHUI WITOP BIOTECH CO., LTD
Tel
+8615255079626
Email
eric@witopchemical.com
Country
China
ProdList
23541
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
7724
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Jinan blalong chemical co. LTD
Tel
2710913286@.com
Email
1513643261@qq.com
Country
China
ProdList
14246
Advantage
58
Hefei fuya biotechnology co. LTD
Tel
18096409024
Email
sales02@foreversyn.com
Country
China
ProdList
1905
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shenzhen ruikai de biotechnology co., ltd.
Tel
0755-61348847 17820674378
Fax
0755-21016893
Email
2682116078@qq.com
Country
China
ProdList
7843
Advantage
58
Nanjing wangzhixing Pharmaceutical Technology Co., Ltd
Tel
15850510341
Fax
025-85722793
Email
shiqingran@wzxchem.com
Country
China
ProdList
3746
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12661
Advantage
58
Molcoo Chemicals Inc.
Tel
18576690171 17386083646
Email
3001006472@qq.com
Country
China
ProdList
11837
Advantage
58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
ProdList
6753
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
Shaanxi Xihua Chemical Industry Co., Ltd
Tel
17691182729 15529505138
Email
1021@dideu.com
Country
China
ProdList
9973
Advantage
58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd
Tel
18502726233; 18502726233
Email
3641133981@qq.com
Country
China
ProdList
9711
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
18616537568
Email
hanfangpharma@126.com
Country
China
ProdList
29971
Advantage
58
Hubei Moco Chemical Co., Ltd.
Tel
18627753421 18627756402
Fax
QQ：3001051413
Email
3001009495@qq.com
Country
China
ProdList
19063
Advantage
58
TLC Pharmaceutical Standards Ltd.
Tel
18012923235
Email
chinasales04@tlcstandards.com.cn
Country
China
ProdList
4921
Advantage
58
Shanghai Hetan Pharmaceutical Technology Co., Ltd.
Tel
18513862380
Email
contact@c12.ai
Country
China
ProdList
3135
Advantage
58
China National Standard Pharmaceutical Corporation Limited
Tel
+8615391658522
Email
overseasales@yongstandards.com
Country
China
ProdList
11922
Advantage
58
Shanghai Ziqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
2453006496@qq.com
Country
CHINA
ProdList
6184
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
--
Fax
--
Email
kexianxun@gmail.com
Country
China
ProdList
1037
Advantage
50
Shanghai Yubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
344843571@qq.com
Country
CHINA
ProdList
6318
Advantage
58
Shanghai yiji industries Co., Ltd.
Tel
--
Fax
--
Email
yiji01@foxmail.com
Country
China
ProdList
6289
Advantage
50
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6025
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6906
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
More
Less

View Lastest Price from (R)-(+)-Ketorolac manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
(R)-(+)-Ketorolac 66635-93-6
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-13

66635-93-6, (R)-(+)-KetorolacRelated Search:

(S)-Ketorolac Ketorolac Impurity 48 Ketorolac Impurity 43 Ketorolac Impurity 31 Ketorolac Impurity 24 (5-chloro-1H-pyrrol-2-yl)-phenylmethanone Ethyl 2-(1H-pyrrol-2-yl)acetate Ketorolac Related Compound A (20 mg) (5-benzoyl-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-2,3-dihydro-1H-pyrrolizine-1-carboxamide) Ethyl-(5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic Ketorolac Impurity 54 4-HYDROXY KETOROLAC Ketorolac tromethamine Ketorolac Impurity 21 KETOROLAC EP IMPURITY H Ketorolac EP IMpurity D 1-Descarboxy Ketorolac Ketorolac EP IMpurity G 2,2'-BIPYRROL

  • Ketorolac R-IsoMer
  • (1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
  • Ketorolac impurity 1/Ketorolac R-Isomer
  • (R)-(+)-Ketorolac
  • (R)-Ketorolac
  • 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1R)-
  • (R)-(+)-Ketorolac ISO 9001：2015 REACH
  • (R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
  • (R)-Ketorolac [(+)-Ketorolac)
  • (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acidQ: What is (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Q: What is the CAS Number of (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Q: What is the storage condition of (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
  • (+)-Ketorolac
  • (R)-Ketorolac,inhibit,Inhibitor,(R) Ketorolac,(R)Ketorolac
  • 66635-93-6
  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals