HOMOVERATRYL CHLORIDE Property

Melting point:

40-43 °C (lit.)

Boiling point:

118-119 °C/0.2 mmHg (lit.)

Density 

1.245 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.5489(lit.)

Flash point:

>230 °F

BRN 

396343

Safety

Hazard Codes 

C

Risk Statements 

34-36/37

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

F 

10-19-21

HazardClass 

8

PackingGroup 

III

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

HOMOVERATRYL CHLORIDE Chemical Properties,Usage,Production

Uses

2-(3,4-Dimethoxyphenyl)acetyl chloride is used as a reactant in the cycloaddition reaction with tetramethoxyethylene in the preparation of novel unsymmetrical squaraines.

Uses

(3,4-Dimethoxyphenyl)acetyl chloride (Homoveratryl chloride) has been used in the preparation of:

• homo veratryl nitrile (HVN)
• isomeric naphthalene sulphonyl compounds, 1- and 2-[{2-(3,4-dimethoxyphenyl)ethyl}methylamino] sulphonyl naphthalenes

Synthesis Reference(s)

Canadian Journal of Chemistry, 35, p. 651, 1957 DOI: 10.1139/v57-094