ChemicalBook > CAS DataBase List > PRAZARELIX
PRAZARELIX
- Product Name
- PRAZARELIX
- CAS No.
- 134457-28-6
- Chemical Name
- PRAZARELIX
- Synonyms
- Azaline B;PRAZARELIX;Prazarelix [inn];D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[(3-amino-1H-1,2,4-triazol-5-yl)amino]-L-phenylalanyl-4-[(3-amino-1H-1,2,4-triazol-5-yl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-
- CBNumber
- CB52448504
- Molecular Formula
- C80H102ClN23O12
- Formula Weight
- 1613.27
- MOL File
- 134457-28-6.mol
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PRAZARELIX Property
- Density
- 1.348±0.06 g/cm3(Predicted)
- pka
- 11.55±0.40(Predicted)
- Sequence
- Ac-{d-Ala<2Nal>}-{d-Phe
}-{d-Ala }-Ser-{Phe }-{d-Phe }-Leu-{Lys }-Pro-{d-Ala} X=3-amino-1H-1,2,4-triazol-5-yl)amino
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PRAZARELIX Chemical Properties,Usage,Production
Uses
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception[1].
References
[1] Samant MP, et al., Novel gonadotropin-releasing hormone antagonists with substitutions at position 5. Biopolymers. 2005;80(2-3):386-91. DOI:10.1002/bip.20195
PRAZARELIX Preparation Products And Raw materials
Raw materials
Preparation Products
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