SULAMSEROD

Product Name: SULAMSEROD
CAS No.: 219757-90-1
Chemical Name: SULAMSEROD
Synonyms: RS-100302;SULAMSEROD;Methanesulfonamide, N-[2-[4-[3-(8-amino-7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-3-oxopropyl]-1-piperidinyl]ethyl]-
CBNumber: CB52451311
Molecular Formula: C19H28ClN3O5S
Formula Weight: 445.96
MOL File: 219757-90-1.mol

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SULAMSEROD Property

Boiling point:: 647.8±65.0 °C(Predicted)
Density: 1.319±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 11.22±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0019424
Product name: SULAMSEROD
Purity: 95.00%
Packaging: 5MG
Price: $500.85
Updated: 2021/12/16

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SULAMSEROD Chemical Properties,Usage,Production

Uses

Sulamserod is a 5-HT4 receptor antagonist, with antiarrhythmic activities.

in vivo

Sulamserod (30 mg/kg) prolongs mean ERP (11568 versus 14667 ms, P,0.01) and wavelength (8.360.9 versus 9.960.8 cm, P,0.01), reduces dispersion of ERP (1565 versus 861 ms, P,0.01), and minimally slows conduction velocity (7264 versus 6765 cm/s, P,0.01) in pigs. Sulamserod produces no ventricular electrophysiological effects. Sulamserod terminates atrial flutter in 6 of 8 animals and atrial fibrillation in 8 of 9 animals and prevents reinduction of sustained tachycardia in all animals^[1].

IC 50

5-HT₄ Receptor

References

[1] Rahme MM, et al. Electrophysiological and antiarrhythmic effects of the atrial selective 5-HT(4) receptor antagonist RS-100302 in experimental atrial flutter and fibrillation. Circulation. 1999 Nov 9;100(19):2010-7. DOI:10.1161/01.cir.100.19.2010

SULAMSEROD Preparation Products And Raw materials

Raw materials

Preparation Products

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SULAMSEROD Suppliers

China 8 United States 2 Global 10

Fan De(Beijing) Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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cjbscvictory

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Beijing Jin Ming Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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Sangon Biotech (Shanghai) Co.,Ltd.

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Biosynth Biological Technology (Suzhou) Co Ltd

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Adooq Bioscience LLC

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219757-90-1, SULAMSERODRelated Search:

1-(4-AMINO-3-CHLORO-PHENYL)-PROPAN-1-ONE 1-(4-Amino-2-hydroxy-phenyl)-propan-1-one (5''-CHLORO-2'',3''-DIMETHOXY)ACETOPHENONE 5-Amino-1,4-benzodioxane SULAMSEROD

SULAMSEROD

RS-100302

Methanesulfonamide, N-[2-[4-[3-(8-amino-7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-3-oxopropyl]-1-piperidinyl]ethyl]-

219757-90-1