3-OXETANECARBOXALDEHYDE, 3-METHYL-
- Product Name
- 3-OXETANECARBOXALDEHYDE, 3-METHYL-
- CAS No.
- 99419-31-5
- Chemical Name
- 3-OXETANECARBOXALDEHYDE, 3-METHYL-
- Synonyms
- 3-methyloxetane-3-carbaldehyde;3-Methyl-3-oxetanecarboxa...;3-Methyl-3-oxetane-carbaldehyde;3-Methyl-3-oxetanecarboxaldehyde;3-methyloxetane-3-carboxaldehyde;3-OXETANECARBOXALDEHYDE, 3-METHYL-;3-Methyl-3-oxetanecarboxaldehyde - [M6233]
- CBNumber
- CB52451669
- Molecular Formula
- C5H8O2
- Formula Weight
- 100.12
- MOL File
- 99419-31-5.mol
3-OXETANECARBOXALDEHYDE, 3-METHYL- Property
- Boiling point:
- 63 °C(Press: 30 Torr)
- Density
- 1.150±0.06 g/cm3(Predicted)
- refractive index
- 1.436
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- form
- solid
- Appearance
- Colorless to light green Liquid
- InChI
- InChI=1S/C5H8O2/c1-5(2-6)3-7-4-5/h2H,3-4H2,1H3
- InChIKey
- DUQGFIKXKISULR-UHFFFAOYSA-N
- SMILES
- O1CC(C)(C=O)C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M219535
- Product name
- 3-Methyloxetane-3-carbaldehyde
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 2H17-1-81
- Product name
- 3-Methyl-3-oxetanecarboxaldehyde
- Packaging
- 1g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- 2H17-1-81
- Product name
- 3-Methyl-3-oxetanecarboxaldehyde
- Packaging
- 5G
- Price
- $280
- Updated
- 2021/12/16
- Product number
- AS12149
- Product name
- 3-Methyloxetane-3-carboxaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $101
- Updated
- 2021/12/16
- Product number
- 2H17-1-81
- Product name
- 3-Methyl-3-oxetanecarboxaldehyde
- Packaging
- 25g
- Price
- $950
- Updated
- 2021/12/16
3-OXETANECARBOXALDEHYDE, 3-METHYL- Chemical Properties,Usage,Production
Synthesis
3143-02-0
99419-31-5
General procedure for the synthesis of 3-methyl-3-formyl-1-oxetane from 3-methyl-3-hydroxymethyl oxetane: 3-methyl oxetan-3-ylmethanol (6.0 g, 58.75 mmol) was dissolved in dichloromethane (117 mL). Trichloroisocyanuric acid (13.93 g, 59.92 mmol) followed by 2,2,6,6-tetramethylpiperidin-1-yloxy (TEMPO) (0.92 g, 5.87 mmol) was added in batches at -5°C. The reaction mixture was then dissolved in dichloromethane (117 mL). The reaction mixture was stirred at -5°C for 20 min, then slowly warmed to room temperature and continued stirring for 20 min. Upon completion of the reaction, the mixture was filtered through a pad of diatomaceous earth (CELITE) and diluted with dichloromethane (200 mL). The organic phase was washed sequentially with saturated aqueous sodium carbonate solution (100 mL), 1N hydrochloric acid (100 mL) and brine (50 mL). Concentration of the organic phase afforded 3-methyl-3-formyl-1-oxetane as an orange oil (4.17 g, 71% yield), which could be used for subsequent reactions without further purification. The product was confirmed by NMR hydrogen spectrum (400 MHz, CDCl3): δ 1.48 (s, 3H), 4.50 (d, 2H, J = 6.34 Hz), 4.88 (d, 2H, J = 6.34 Hz), 9.95 (s, 1H).
References
[1] Organic and Biomolecular Chemistry, 2018, vol. 16, # 11, p. 1843 - 1850
[2] Patent: WO2012/74761, 2012, A1. Location in patent: Page/Page column 19-20
[3] Patent: US2014/309208, 2014, A1. Location in patent: Paragraph 0363; 0365
[4] Patent: WO2012/41014, 2012, A1. Location in patent: Page/Page column 123-124
[5] Patent: WO2012/40923, 2012, A1. Location in patent: Page/Page column 105
3-OXETANECARBOXALDEHYDE, 3-METHYL- Preparation Products And Raw materials
Raw materials
Preparation Products
3-OXETANECARBOXALDEHYDE, 3-METHYL- Suppliers
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View Lastest Price from 3-OXETANECARBOXALDEHYDE, 3-METHYL- manufacturers
- Product
- 3-OXETANECARBOXALDEHYDE, 3-METHYL- 99419-31-5
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-10