3-AMINO-5-BROMO-2-NITROPYRIDINE
Uses- Product Name
- 3-AMINO-5-BROMO-2-NITROPYRIDINE
- CAS No.
- 433226-05-2
- Chemical Name
- 3-AMINO-5-BROMO-2-NITROPYRIDINE
- Synonyms
- 5-BroMo-2-nitropyridin-3-aMine;5-BroMo-2-nitro-3-pyridinaMine;3-AMINO-5-BROMO-2-NITROPYRIDINE;3-Pyridinamine, 5-bromo-2-nitro-;5-Bromo-2-nitro-pyridin-3-ylamine
- CBNumber
- CB52455278
- Molecular Formula
- C5H4BrN3O2
- Formula Weight
- 218.01
- MOL File
- 433226-05-2.mol
3-AMINO-5-BROMO-2-NITROPYRIDINE Property
- Boiling point:
- 404.0±40.0 °C(Predicted)
- Density
- 1.929±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- -3.55±0.25(Predicted)
- form
- powder
- color
- Very dark yellow
- InChI
- InChI=1S/C5H4BrN3O2/c6-3-1-4(7)5(8-2-3)9(10)11/h1-2H,7H2
- InChIKey
- GOXZJSIRAHNQQG-UHFFFAOYSA-N
- SMILES
- C1([N+]([O-])=O)=NC=C(Br)C=C1N
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- B673883
- Product name
- 5-bromo-2-nitropyridin-3-amine
- Packaging
- 100mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- 4H55-9-32
- Product name
- 3-Amino-5-bromo-2-nitropyridine
- Packaging
- 250mg
- Price
- $352
- Updated
- 2021/12/16
- Product number
- HCH0361358
- Product name
- 5-BROMO-2-NITROPYRIDIN-3-AMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.93
- Updated
- 2021/12/16
- Product number
- 4H55-9-32
- Product name
- 3-Amino-5-bromo-2-nitropyridine
- Packaging
- 500mg
- Price
- $637
- Updated
- 2021/12/16
- Product number
- 188721
- Product name
- 5-Bromo-2-nitropyridin-3-amine
- Packaging
- 500mg
- Price
- $676
- Updated
- 2021/12/16
3-AMINO-5-BROMO-2-NITROPYRIDINE Chemical Properties,Usage,Production
Uses
3-Amino-5-bromo-2-nitropyridine is an organic intermediate that can be prepared from 3-amino-5-bromopyridine as a raw material by first protecting the amino group, then nitrifying, and finally deprotecting.
Synthesis
152684-25-8
433226-05-2
General procedure for the synthesis of 3-amino-5-bromo-2-nitropyridine from ethyl (5-bromo-2-nitropyridin-3-yl)carbamate: to a solution of ethyl (5-bromo-2-nitropyridin-3-yl)carbamate (1.5 g, 5.2 mmol) in tetrahydrofuran (10 ml) was added a solution of potassium hydroxide (582 mg, 10.4 mmol) in water (5.0 ml) solution and the reaction mixture was stirred at 90°C overnight. After completion of the reaction, water was added to the mixture and precipitate was precipitated, the precipitate was collected by filtration, washed with water and then dried under reduced pressure to give 3-amino-5-bromo-2-nitropyridine (1.1 g, 95% yield).
References
[1] Patent: US2014/128391, 2014, A1. Location in patent: Paragraph 0226; 0231; 0232
[2] Patent: US2004/82583, 2004, A1
[3] Patent: US9242996, 2016, B2. Location in patent: Page/Page column 82; 83
[4] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 19, p. 5913 - 5917
[5] Patent: WO2017/7756, 2017, A1. Location in patent: Paragraph 224
3-AMINO-5-BROMO-2-NITROPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
3-AMINO-5-BROMO-2-NITROPYRIDINE Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from 3-AMINO-5-BROMO-2-NITROPYRIDINE manufacturers
- Product
- 5-Bromo-2-nitropyridin-3-amine 433226-05-2
- Price
- US $1.60-6.60/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19
- Product
- 3-AMINO-5-BROMO-2-NITROPYRIDINE 433226-05-2
- Price
- US $0.10/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10g,100g,1kg
- Release date
- 2020-01-10