2,3-Diamino-4-chloropyridine
- Product Name
- 2,3-Diamino-4-chloropyridine
- CAS No.
- 24484-98-8
- Chemical Name
- 2,3-Diamino-4-chloropyridine
- Synonyms
- 4-Chloro-2,3-pyridinediamine;4-chloro-2,3-diaMinopyridine;2,3-Diamino-4-chloropyrid...;2,3-Diamino-4-chloropyridine;2,3-PyridinediaMine, 4-chloro-;2,3-Diamino-4-chloropyridine 97%;2,3-Diamino-4-chloropyridine ISO 9001：2015 REACH
- CBNumber
- CB52462270
- Molecular Formula
- C5H6ClN3
- Formula Weight
- 143.57
- MOL File
- 24484-98-8.mol
2,3-Diamino-4-chloropyridine Property
- Melting point:
- >158°C (dec.)
- Boiling point:
- 314.0±37.0 °C(Predicted)
- Density
- 1.447±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- Chloroform (Slightly, Sonicated), DMSO (Slightly), Ethyl Acetate (Slightly, Sonicated)
- pka
- 5.68±0.47(Predicted)
- form
- Solid
- color
- Pale Grey to Light Beige
- InChI
- InChI=1S/C5H6ClN3/c6-3-1-2-9-5(8)4(3)7/h1-2H,7H2,(H2,8,9)
- InChIKey
- APGDUAJEMRMIJU-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=CC(Cl)=C1N
Safety
- RIDADR
- UN2671
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D415090
- Product name
- 2,3-Diamino-4-chloropyridine
- Packaging
- 1g
- Price
- $85
- Updated
- 2021/12/16
- Product number
- 3H32-5-AY
- Product name
- 2,3-Diamino-4-chloropyridine
- Packaging
- 1g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- CAPOC13673
- Product name
- 4-Chloropyridine-2,3-diamine
- Purity
- 95%
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- CAPOC13673
- Product name
- 4-Chloropyridine-2,3-diamine
- Purity
- 95%
- Packaging
- 5g
- Price
- $188
- Updated
- 2021/12/16
- Product number
- FC163646
- Product name
- 4-Chloropyridine-2,3-diamine
- Packaging
- 1g
- Price
- $200
- Updated
- 2021/12/16
2,3-Diamino-4-chloropyridine Chemical Properties,Usage,Production
Synthesis
6980-08-1
24484-98-8
The general procedure for the synthesis of 2,3-diamino-4-chloropyridine from 2-amino-3-nitro-4-chloropyridine was as follows: 2-amino-3-nitro-4-chloropyridine (2 g, 11.52 mmol, 1.00 equiv) was dissolved in a mixture of 20 mL of solvent of n-propanol and water in a 100 mL round bottom flask. Iron powder (3.23 g, 57.84 mmol, 5.02 eq.) and ammonium chloride (3.06 g, 57.21 mmol, 4.96 eq.) were sequentially added to the reaction system at room temperature. The reaction mixture was stirred at 70 °C for 2 hours. Upon completion of the reaction, the mixture was cooled to room temperature and thermally filtered through a diatomaceous earth pad. The filtrate was concentrated under reduced pressure to afford the target product 2,3-diamino-4-chloropyridine (1.6 g, 97% yield) as a black solid.
References
[1] Patent: US2016/96834, 2016, A1. Location in patent: Paragraph 0322
[2] Patent: WO2014/128465, 2014, A1. Location in patent: Page/Page column 54; 55
[3] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 23, p. 6567 - 6571
[4] Patent: US5298518, 1994, A
[5] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 15, p. 4344 - 4353
2,3-Diamino-4-chloropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,3-Diamino-4-chloropyridine manufacturers
- Product
- 2,3-Diamino-4-chloropyridine 24484-98-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-06
- Product
- 2,3-Diamino-4-chloropyridine 24484-98-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 2,3-Diamino-4-chloropyridine 24484-98-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09