2-ACETYL-3-CHLOROPYRIDINE
- Product Name
- 2-ACETYL-3-CHLOROPYRIDINE
- CAS No.
- 131109-75-6
- Chemical Name
- 2-ACETYL-3-CHLOROPYRIDINE
- Synonyms
- 2-ACETYL-3-CHLOROPYRIDINE;1-(3-Chloro-2-pyridyl)ethanone;1-(3-chloropyridin-2-yl)ethanone;Ethanone, 1-(3-chloro-2-pyridinyl)-;1-(3-chloropyridin-2-yl)ethan-1-one
- CBNumber
- CB52465756
- Molecular Formula
- C7H6ClNO
- Formula Weight
- 155.58
- MOL File
- 131109-75-6.mol
2-ACETYL-3-CHLOROPYRIDINE Property
- storage temp.
- Inert atmosphere,Room Temperature
- form
- liquid
- color
- Orange
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 4H17-5-2A
- Product name
- 1-(3-Chloropyridin-2-yl)ethanone
- Packaging
- 250mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 5776AA
- Product name
- 1-(3-Chloropyridin-2-yl)ethanone
- Packaging
- 1g
- Price
- $167
- Updated
- 2021/12/16
- Product number
- 4H17-5-2A
- Product name
- 1-(3-Chloropyridin-2-yl)ethanone
- Packaging
- 1g
- Price
- $210
- Updated
- 2021/12/16
- Product number
- 112962
- Product name
- 2-Acetyl-3-chloropyridine
- Packaging
- 1g
- Price
- $473
- Updated
- 2021/12/16
- Product number
- 112962
- Product name
- 2-Acetyl-3-chloropyridine
- Packaging
- 5g
- Price
- $1300
- Updated
- 2021/12/16
2-ACETYL-3-CHLOROPYRIDINE Chemical Properties,Usage,Production
Synthesis
75-16-1
38180-46-0
131109-75-6
The general procedure for the synthesis of 1-(3-chloropyridin-2-yl)ethanone from methylmagnesium bromide and 3-chloro-2-cyanopyridine was as follows: to a mixture of 54 g of 3-chloro-2-cyanopyridine and 300 mL of tetrahydrofuran (THF) was added slowly and dropwise 500 g of 1 M methylmagnesium bromide in a THF solution under ice bath cooling conditions. Keeping the ice bath cool, the reaction mixture was stirred for 2 hours. Subsequently, the reaction mixture was slowly added to a 2 N hydrochloric acid solution under ice bath cooling and stirring was continued for 30 minutes. The pH of the mixture was adjusted to 8 with 1 N aqueous sodium hydroxide solution, after which it was extracted with ethyl acetate. The organic layer was washed with saturated brine and dried with anhydrous sodium sulfate. Finally, the organic layer was concentrated by decompression to give 58 g of intermediate (12-1).
References
[1] Patent: JP2017/36339, 2017, A. Location in patent: Paragraph 0178
[2] Patent: US2017/295787, 2017, A1. Location in patent: Paragraph 0639
[3] Patent: US2017/305896, 2017, A1. Location in patent: Paragraph 0621
2-ACETYL-3-CHLOROPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-ACETYL-3-CHLOROPYRIDINE Suppliers
- Tel
- 13526569071
- sales@leadmedpharm.com
- Country
- China
- ProdList
- 7892
- Advantage
- 64
- Tel
- 020-82185713,82185709 13418171485
- Fax
- 020-82185696
- sales@chem-stone.com
- Country
- China
- ProdList
- 744
- Advantage
- 56
- Tel
- 18151128828
- Fax
- -
- hc-sales@foxmail.com
- Country
- China
- ProdList
- 2647
- Advantage
- 55
- Tel
- +49 5662 408730
- Fax
- +49 5662 4087320
- info@synchem.de
- Country
- Germany
- ProdList
- 4705
- Advantage
- 70
- Tel
- sales@ahpharmatech.com
- Country
- China
- ProdList
- 5734
- Advantage
- 55
- Tel
- 025-66028182 18626450290
- yftan@aikonchem.com
- Country
- China
- ProdList
- 16679
- Advantage
- 50
- Tel
- 13391076197
- tombiopharma@163.com
- Country
- China
- ProdList
- 4987
- Advantage
- 55
- Tel
- 010-56330744 18310155299
- Fax
- 010-56330744
- sales@labter.com.cn
- Country
- China
- ProdList
- 20000
- Advantage
- 55
- Tel
- 0371-88888888 272369594
- Fax
- QQ:272369594
- 2723695949@qq.com
- Country
- China
- ProdList
- 4958
- Advantage
- 50
- Tel
- 0371-53765687 18937137882
- Fax
- QQ:2885373884
- 2853979813@qq.com
- Country
- China
- ProdList
- 7992
- Advantage
- 55
View Lastest Price from 2-ACETYL-3-CHLOROPYRIDINE manufacturers
- Product
- 2-ACETYL-3-CHLOROPYRIDINE 131109-75-6
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-25