ChemicalBook > CAS DataBase List > METHYL 3-OXOHEPTANOATE

METHYL 3-OXOHEPTANOATE

Product Name
METHYL 3-OXOHEPTANOATE
CAS No.
39815-78-6
Chemical Name
METHYL 3-OXOHEPTANOATE
Synonyms
VEM;Valeric METHYL 3-OXOENANTHATE;METHYL VALERYLACETATE;METHYL 3-OXOHEPTANOATE;Methyl3-Oxoheptanoate>Methyl valerylacetate, VEM;3-OXOENANTHIC ACID METHYL ESTER;3-OXOHEPTANOIC ACID METHYL ESTER;3-Ketoenanthic acid methyl ester
CBNumber
CB5246810
Molecular Formula
C8H14O3
Formula Weight
158.2
MOL File
39815-78-6.mol
More
Less

METHYL 3-OXOHEPTANOATE Property

Boiling point:
90-91 °C15 hPa(lit.)
Density 
0.994 g/mL at 20 °C(lit.)
refractive index 
1.4280-1.4310
Flash point:
95 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
pka
10.63±0.46(Predicted)
color 
Clear Colorless
InChIKey
CZTKGERSDUGZPQ-UHFFFAOYSA-N
More
Less

Safety

Safety Statements 
24/25
WGK Germany 
-
HS Code 
29159000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
O0246
Product name
Methyl 3-Oxoheptanoate
Purity
>95.0%(GC)
Packaging
25mL
Price
$95
Updated
2025/07/31
TRC
Product number
M324730
Product name
Methyl 3-Oxoheptanoate
Packaging
5g
Price
$110
Updated
2021/12/16
TRC
Product number
M324730
Product name
Methyl 3-Oxoheptanoate
Packaging
100g
Price
$525
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
41513
Product name
Methyl 3-Oxoheptanoate
Packaging
5G
Price
$610
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0010888
Product name
METHYL 3-OXOHEPTANOATE
Purity
95.00%
Packaging
25ML
Price
$1123.24
Updated
2021/12/16
More
Less

METHYL 3-OXOHEPTANOATE Chemical Properties,Usage,Production

Chemical Properties

Colorless to pale yellow transparent liquid

Uses

Methyl 3-oxoheptanoate is used as a reagent to synthesize 4-oxymethyl-1,2-dioxanes, compounds that exhibit potent anti-malarial activity. Methyl 3-oxoheptanoate is also used as a reagent to prepare a series of substituted cyclopenta-[d]-pyrimidines, compounds that act as anti-microtubule (anticancer) agents.

Synthesis

7732-18-5

107-08-4

105-45-3

39815-78-6

To a 200 mL solution of anhydrous tetrahydrofuran (THF) containing 14 mL of diisopropylamine was slowly added 59 mL of a 1.6 M butyllithium hexane solution under nitrogen protection and stirred for 20 minutes. Subsequently, 9.3 mL of methyl acetoacetate was added dropwise at 0°C and stirring was continued for 30 minutes. Another 54 mL of hexane solution of 1.6 M butyllithium was added slowly and stirred for 30 minutes before 8.4 mL of 1-iodopropane was added dropwise to the dark orange solution. The reaction mixture was gradually warmed to room temperature and stirring was continued for 30 minutes. A solution diluted by 50 mL of 37% hydrochloric acid and 100 mL of water was added slowly and dropwise while keeping the temperature below 15 °C. Upon completion of the reaction, the reaction mixture was extracted with ether (Et2O). The organic phase was washed with saturated sodium chloride (NaCl) solution, dried over anhydrous sodium sulfate (Na2SO4) and concentrated to dryness under reduced pressure. The residue was purified by column chromatography (eluent: ethyl acetate/hexane=1:9) to afford 8.3 g of the clear oily product methyl 3-oxoheptanoate in 61% yield.1H-NMR (200 MHz, CDCl3) δ: 0.90 (t, 3H), 1.22-1.65 (m, 4H), 2.53 (t, 2H), 3.44 (s, 2H), 3.73 (s, 3H).

References

[1] Patent: US5565464, 1996, A

METHYL 3-OXOHEPTANOATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

METHYL 3-OXOHEPTANOATE Suppliers

Americas 1 China 87 Europe 1 Germany 3 India 3 Japan 1 Slovakia 1 Switzerland 1 United Kingdom 4 United States 13 Global 115
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2805
Advantage
65
Weifang Dudeli Chemical Industry Co.,LTD.
Tel
+86-536-3419010
Fax
+86-536-3418766
Country
China
ProdList
9
Advantage
64
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16075
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
Advantage
57
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5674
Advantage
50
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3495
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shijiazhuang Yesheng Chemical Technology Co., Ltd
Tel
18031147013 18031147013;
Fax
0311-68030586
Email
yeshengchemical@163.com
Country
China
ProdList
2607
Advantage
58
Dalian lichuang Chemical Co., Ltd
Tel
0411-0411-00000000 13644282108
Fax
-
Email
3500508746@qq.com
Country
China
ProdList
2896
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
Advantage
60
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10330
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ：2853979817
Email
2853979817@qq.com
Country
China
ProdList
9988
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
TCI Chemicals
Tel
021-67121386, 800-988-0390
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
5391
Advantage
58
Suzhou Rovathin Foreign Trade Co.,Ltd
Tel
0512-65816829 18662214788
Fax
0512-65816829
Email
info@rovathin.com.cn
Country
China
ProdList
9987
Advantage
58
Guangzhou TongYi biochemistry technology Co.,LTD
Tel
+8613073028829
Email
tongyibiochem@163.com
Country
China
ProdList
2995
Advantage
58
Hubei Ipure Biology Co., Ltd
Tel
+8613367258412
Fax
18062427325
Email
ada@ipurechemical.com
Country
China
ProdList
10237
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
8025
Advantage
58
SIMAGCHEM CORP
Tel
+86-5922680277 +86-13806087780
Email
sale@simagchem.com
Country
China
ProdList
17346
Advantage
58
Chongqing Yuzhiquan Biological Technology Co., Ltd.
Tel
18306022109
Fax
QQ:2966918840
Email
3236923470@qq.com
Country
China
ProdList
300
Advantage
58
Hebei Chuanghai Biotechnology Co., Ltd
Tel
+8615350571055
Fax
whatapp+8619930503282
Email
Sibel@chuanghaibio.com
Country
China
ProdList
8768
Advantage
58
Xiamen AmoyChem Co., Ltd
Tel
+86-86-5926051114 +8615060885618
Email
sales@amoychem.com
Country
China
ProdList
6369
Advantage
58
Shanghai Hongshun Biological Technology Co., Ltd.
Tel
15901914505 15901914505;
Fax
021-54389085
Email
3187892335@qq.com
Country
China
ProdList
9889
Advantage
58
Wuhan xinyangruihe Chemical Technology Co., Ltd.
Tel
153-07155313 15307155313
Fax
QQ：2274366233
Email
2274366233@qq.com
Country
China
ProdList
999
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
Shanghai Qianlai Pharmaceutical Technology Co., Ltd.
Tel
021-57216911 17740831186
Email
482109853@qq.com
Country
China
ProdList
462
Advantage
58
CHG Opto-Electronic Corporation Limited
Tel
2537653158 16621191650
Fax
QQ 2537653158
Email
2537653158@qq.com
Country
China
ProdList
7300
Advantage
58
Dongying new direction biology science and technology co., ltd
Tel
13371419997
Email
sqyu@newplace.com.cn
Country
China
ProdList
6
Advantage
58
Mainchem Co., Ltd.
Tel
--
Fax
--
Email
sarah@mainchem.com
Country
China
ProdList
6547
Advantage
58
Henan Lavoisier Chemical Products Co. Ltd
Tel
0371-63682289 18625781376
Fax
18625781376
Email
jacschem@163.com
Country
China
ProdList
4967
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
Beijing yanruicheng Pharmaceutical Technology Co., Ltd
Tel
18616022633
Email
1094628792@qq.com
Country
China
ProdList
340
Advantage
58
More
Less

View Lastest Price from METHYL 3-OXOHEPTANOATE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
METHYL 3-OXOHEPTANOATE 39815-78-6
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2025-03-14
Career Henan Chemical Co
Product
Methyl 3-Oxoheptanoate 39815-78-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons
Release date
2020-02-14

39815-78-6, METHYL 3-OXOHEPTANOATERelated Search:

DIETHYL 3-OXOPIMELATE ALLOXYDIM-SODIUM AFLATOXIN M2 AFLATOXIN B2 Aflatoxin 2,5-dioxo-1,4-cyclohexanedicarboxylic acid dimethyl ester Diethyl succinosuccinate Ethyl 2-oxocyclohexanecarboxylate 2-METHOXYCARBONYLCYCLOHEXANONE Methyl heptanoate ETHYL 3-(1-ADAMANTYL)-3-OXOPROPIONATE METHYL 2-OXO-1-CYCLOHEPTANECARBOXYLATE ETHYL 4-METHYL-2-CYCLOHEXANONE-1-CARBOXYLATE ETHYL ISOAMYLACETOACETATE methyl 3-oxodecanoate AFLATOXIN B2A picromycin ETHYL STEAROYLACETATE

  • METHYL 3-OXOENANTHATE
  • METHYL 3-OXOHEPTANOATE
  • METHYL VALERYLACETATE
  • 3-KETOHEPTANOIC ACID METHYL ESTER
  • 3-OXOENANTHIC ACID METHYL ESTER
  • 3-OXOHEPTANOIC ACID METHYL ESTER
  • VEM
  • Valeric&nbsp
  • 3-Ketoheptanoic Acid Methyl Ester Methyl 3-Oxoenanthate 3-Oxoenanthic Acid Methyl Ester 3-Oxoheptanoic Acid Methyl Ester
  • METHYL 3-OXOHEPTANOATE, WACKER QUALITY
  • 3-OXOENANTHIC ACID METHYL ESTER 95+%
  • Methyl valerylacetate, VEM
  • 3-Ketoenanthic acid methyl ester
  • Methyl3-Oxoheptanoate&gt
  • Heptanoic acid, 3-oxo-, methyl ester
  • METHYL 3-OXOHEPTANOATE ISO 9001：2015 REACH
  • Heptanoic acid, 3-oxo-, methyl ester (6CI, 9CI, ACI)
  • 3-oxo-Heptanoic acid methyl ester (6CI 9CI ACI)
  • 39815-78-6
  • CH3CH23COCH2COOCH3
  • Organic Building Blocks
  • Esters
  • C8 to C9
  • Carbonyl Compounds
  • Building Blocks