ChemicalBook > CAS DataBase List > BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTER

BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTER

Product Name: BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTER
CAS No.: 199850-56-1
Chemical Name: BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTER
Synonyms: Methyl 2-aMino-4-chloro-5-iodobenzoate;Methyl 4-chloro-5-iodoanthranilate;2-AMino-4-chloro-5-iodo-benzoic acid Methyl ester;BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTER
CBNumber: CB52468676
Molecular Formula: C8H7ClINO2
Formula Weight: 311.5
MOL File: 199850-56-1.mol

Less

BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTER Property

Boiling point:: 369.2±42.0 °C(Predicted)
Density: 1.903
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 0.99±0.10(Predicted)
Appearance: Off-white to gray Solid

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

TRC

Product number: M331750
Product name: Methyl2-Amino-4-chloro-5-iodobenzoate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: CS-0041075
Product name: Methyl2-amino-4-chloro-5-iodobenzoate
Packaging: 5g
Price: $153
Updated: 2021/12/16

Crysdot

Product number: CD12098816
Product name: Methyl2-amino-4-chloro-5-iodobenzoate
Purity: 95+%
Packaging: 5g
Price: $168
Updated: 2021/12/16

Chemenu

Product number: CM155772
Product name: methyl2-amino-4-chloro-5-iodobenzoate
Purity: 95%
Packaging: 5g
Price: $196
Updated: 2021/12/16

Alichem

Product number: 199850561
Product name: Methyl2-amino-4-chloro-5-iodobenzoate
Packaging: 5g
Price: $224.7
Updated: 2021/12/16

Less

BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTER Chemical Properties,Usage,Production

Synthesis

5900-58-3

199850-56-1

General procedure for the synthesis of methyl 4-chloro-5-iodo-2-aminobenzoate from methyl 2-amino-4-chlorobenzoate: Methyl 2-amino-4-chlorobenzoate (50 g, 0.27 mol) was added to a solution of anhydrous ethanol (2.5 L) containing iodine (68 g, 0.27 mol) and silver sulfate (84 g, 0.27 mol). The reaction mixture was stirred at room temperature for 45 minutes. Subsequently, the reaction mixture was filtered through a Celite pad to remove insoluble impurities. The filtrate was concentrated under reduced pressure and the residue was dissolved in ethyl acetate (2 L) and washed sequentially with saturated aqueous sodium bicarbonate (3 x 400 mL), water (3 x 400 mL) and brine. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford the target product methyl 2-amino-4-chloro-5-iodobenzoate (85 g, 99% yield).

References

[1] Journal of Labelled Compounds and Radiopharmaceuticals, 2003, vol. 46, # 10, p. 993 - 1000
[2] Chemical Communications, 2017, vol. 53, # 62, p. 8735 - 8738
[3] Patent: WO2010/65134, 2010, A1. Location in patent: Page/Page column 60-61
[4] Patent: WO2015/54572, 2015, A1. Location in patent: Page/Page column 261; 262
[5] Patent: WO2012/119978, 2012, A1. Location in patent: Page/Page column 50

BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Less

BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTER Suppliers

China 41 India 1 United States 2 Global 44

Atop-Pharma (Shanghai) Technology Co., Ltd.

Tel: +86 (21) 5196-9732
Fax: +86 (21) 5196-9733
Country: China
ProdList: 996
Advantage: 57

Chiba Pharmaceutical Science and technology Co, Ltd.

Tel: 0531-81313138 13066006660
Fax: QQ: 3366077777
Email: chibapharm@foxmail.com
Country: China
ProdList: 3991
Advantage: 55

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 86(512)5235 8471 17715136450
Fax: 86(512)5235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 4169
Advantage: 58

Xinyanhe Pharmatech Co.,Ltd

Tel: 0519-85252752 15366845260
Fax: 86-0519-85683352
Email: taihuaren@vip.163.com
Country: China
ProdList: 1124
Advantage: 58

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
Fax: 17321281695
Email: sale@amkchem.com
Country: China
ProdList: 15136
Advantage: 55

Quzhou AMK BioTech Co., Ltd

Tel: 0570-3081766 18357083060
Fax: 0570-3072337
Email: sales@qzamkbio.com
Country: China
ProdList: 1051
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Jiaxing Deyi Chemical Co., Ltd.

Tel: 86-0573-85866609 13325730825
Fax: 0573-85866609
Email: 945717149@qq.com
Country: China
ProdList: 8595
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 16027
Advantage: 58

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Suzhou Xiya Pharmaceutical Co., Ltd.

Tel: 0512-87819718 18912655635
Email: 2587879032@qq.com
Country: China
ProdList: 1403
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55055611 18137792234
Fax: QQ：3002694073
Email: 3002694073@qq.com
Country: China
ProdList: 9987
Advantage: 58

Xinyi Kaiwu Chemical Technology Co., Ltd.

Tel: 0516-0516-88997009 18651776937
Email: 4164357@qq.com
Country: China
ProdList: 3204
Advantage: 58

CR Corporation Limited

Tel: +8613062833949
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 8645
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd

Tel: 037188900765 18037465274
Fax: QQ3430974218
Email: enyawanglei@sina.cn
Country: China
ProdList: 13966
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Shanghai Xuerong Chemical Technology Co., LTD

Tel: 18201727566
Fax: QQ:230497258
Email: 230497258@qq.com
Country: China
ProdList: 513
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Shaanxi Yudingzhuo Medical Technology Co., Ltd.

Tel: 18992018580 18165105898
Fax: QQ:1617857088
Email: 13608210612@163.com
Country: China
ProdList: 2984
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Henan Dowon Chemical Technology Co., Ltd.

Tel: 16696119288
Email: 779113375@qq.com
Country: China
ProdList: 7236
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Nanjing Yinshiqi Biotechnology Co. LTD

Tel: 18727012071
Email: 361921159@qq.com
Country: China
ProdList: 301
Advantage: 58

Zhengzhou JACS Chemical Product Co., LTD

Tel: 0371-86259281 13223061139
Email: 893596907@qq.com
Country: China
ProdList: 7993
Advantage: 58

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 17715136450
Email: 2439673774@qq.com
Country: China
ProdList: 15647
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Changzhou Pacific SynthForm Sciences Co., Ltd.

Tel: 18961173882
Email: mia@psfscience.com
Country: China
ProdList: 999
Advantage: 58

Shanghai Fengluan Biotechnology Co., LTD

Tel: 13357659136
Email: jing.z@fengluanbiotech.com
Country: China
ProdList: 500
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 33024
Advantage: 60

Changzhou Anxuan Chemical Co., Ltd

Tel: +86-0519-89882563 +86-18961279162
Email: andy@anxuanchem.com
Country: China
ProdList: 4327
Advantage: 58

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

Nanjing Fred Technology Co., Ltd

Tel: +86-25-84696168 +86-15380713688
Email: Austin@fredbio.com
Country: China
ProdList: 2428
Advantage: 58

Aromsyn Co., Ltd.

Tel: +86-0571-85585865 +8613336024896
Email: CB@aromsyn.com
Country: China
ProdList: 19183
Advantage: 58

199850-56-1, BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTERRelated Search:

BENZOIC ACID, 2-AMINO-4-CHLORO-5-IODO-, METHYL ESTER

Methyl 4-chloro-5-iodoanthranilate

2-AMino-4-chloro-5-iodo-benzoic acid Methyl ester

Methyl 2-aMino-4-chloro-5-iodobenzoate

199850-56-1