7-Amino-5-fluoroindolin-2-one

Product Name: 7-Amino-5-fluoroindolin-2-one
CAS No.: 945381-62-4
Chemical Name: 7-Amino-5-fluoroindolin-2-one
Synonyms: 7-AMino-5-fluoro-2-oxyindole;7-Amino-5-fluoroindolin-2-one;7-amino-5-fluoro-1,3-dihydro-indol-2-one;7-aMino-5-fluoro-1,3-dihydro-2H-Indol-2-one;2H-Indol-2-one, 7-amino-5-fluoro-1,3-dihydro-
CBNumber: CB52471544
Molecular Formula: C8H7FN2O
Formula Weight: 166.15
MOL File: 945381-62-4.mol

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7-Amino-5-fluoroindolin-2-one Property

Boiling point:: 383.5±42.0 °C(Predicted)
Density: 1.413±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 12.52±0.20(Predicted)
Appearance: Brown to reddish brown Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A636710
Product name: 7-Amino-5-fluoro-1,3-dihydro-2H-indol-2-one
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA104789
Product name: 7-Amino-5-fluoro-1,3-dihydroindol-2-one
Packaging: 50mg
Price: $200
Updated: 2021/12/16

Apolloscientific

Product number: PC201382
Product name: 7-Amino-5-fluoroindolin-2-one
Purity: 95+%
Packaging: 100mg
Price: $67
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA104789
Product name: 7-Amino-5-fluoro-1,3-dihydroindol-2-one
Packaging: 10mg
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA104789
Product name: 7-Amino-5-fluoro-1,3-dihydroindol-2-one
Packaging: 25mg
Price: $125
Updated: 2021/12/16

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7-Amino-5-fluoroindolin-2-one Chemical Properties,Usage,Production

Synthesis

1082990-05-3

945381-62-4

Step 2: 5-Fluoro-7-nitro-1,3-dihydroindol-2-one (20a, 4.0 g, 20 mmol) was dissolved in 200 mL of acetic acid and palladium/activated carbon catalyst (1.0 g, 5%) was added with stirring at room temperature. The reaction mixture was stirred continuously under hydrogen atmosphere. The reaction progress was monitored by thin layer chromatography (TLC) and stopped when the feedstock completely disappeared. The reaction mixture was filtered to remove the catalyst and the filtrate was concentrated under reduced pressure to afford the white solid product 7-amino-5-fluoro-1,3-dihydroindol-2-one (20b, 3.2 g, 97.5% yield).

References

[1] Patent: US2010/75952, 2010, A1. Location in patent: Page/Page column 56
[2] Patent: EP2157093, 2010, A1. Location in patent: Page/Page column 51

7-Amino-5-fluoroindolin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Amino-5-fluoroindolin-2-one Suppliers

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945381-62-4, 7-Amino-5-fluoroindolin-2-oneRelated Search:

7-Amino-5-fluoroindolin-2-one

7-amino-5-fluoro-1,3-dihydro-indol-2-one

7-aMino-5-fluoro-1,3-dihydro-2H-Indol-2-one

7-AMino-5-fluoro-2-oxyindole

2H-Indol-2-one, 7-amino-5-fluoro-1,3-dihydro-

945381-62-4