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2-Amino-4-bromobenzamide

Product Name
2-Amino-4-bromobenzamide
CAS No.
112253-70-0
Chemical Name
2-Amino-4-bromobenzamide
Synonyms
4-Bromoanthranilamide;2-Amino-4-bromobenzamide;Benzamide, 2-amino-4-bromo-
CBNumber
CB52488935
Molecular Formula
C7H7BrN2O
Formula Weight
215.05
MOL File
112253-70-0.mol
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2-Amino-4-bromobenzamide Property

Melting point:
176-177℃
Boiling point:
318.8±27.0 °C(Predicted)
Density 
1.698±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
solid
pka
15.48±0.50(Predicted)
color 
Beige
InChI
InChI=1S/C7H7BrN2O/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,9H2,(H2,10,11)
InChIKey
OFXMSVAQRRUVHA-UHFFFAOYSA-N
SMILES
C(N)(=O)C1=CC=C(Br)C=C1N
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Safety

Risk Statements 
43
Safety Statements 
36/37
HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
BBO000418
Product name
2-Amino-4-bromobenzamide
Packaging
1 g
Price
$259
Updated
2025/07/31
TRC
Product number
A601570
Product name
2-Amino-4-bromobenzamide
Packaging
2.5g
Price
$715
Updated
2021/12/16
AK Scientific
Product number
Y7066
Product name
2-Amino-4-bromobenzamide
Packaging
5g
Price
$577
Updated
2021/12/16
Matrix Scientific
Product number
144900
Product name
2-Amino-4-bromobenzamide
Purity
95%
Packaging
500mg
Price
$1107
Updated
2021/12/16
Apolloscientific
Product number
OR315541
Product name
2-Amino-4-bromobenzamide
Packaging
1g
Price
$203
Updated
2021/12/16
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2-Amino-4-bromobenzamide Chemical Properties,Usage,Production

Uses

2-Amino-4-bromobenzamide is a useful synthetic compound.

Synthesis

20776-50-5

112253-70-0

The general procedure for the synthesis of 2-amino-4-bromobenzamide from 2-amino-4-bromobenzoic acid was as follows: 2-amino-4-bromobenzoic acid (10 g, 46.3 mmol) was dissolved in tetrahydrofuran (THF, 10 mL) at room temperature, 1-hydroxybenzotriazole (HOBT, 16.30 g, 106 mmol) and 1-ethyl-(3- dimethylaminopropyl)carbodiimide hydrochloride (EDC, 20.41 g, 106 mmol). Subsequently, ammonia (30 mL, 1386 mmol) was slowly added to the reaction system and the reaction was stirred at 25 °C for 30 min. The reaction was continued with stirring at the same temperature for 18 hours. Upon completion of the reaction, ethyl acetate (EtOAc, 200 mL) was added to the mixture, followed by concentration under reduced pressure to remove the solvent. The resulting organic phase was washed with saturated aqueous sodium bicarbonate (100 mL × 3) and dried with anhydrous sodium sulfate (Na2SO4). Finally, the solvent was removed by distillation under reduced pressure to afford the target product 2-amino-4-bromobenzamide (5.5 g, 24.55 mmol) in 53% yield.

References

[1] Patent: WO2012/13643, 2012, A1. Location in patent: Page/Page column 48
[2] Patent: WO2017/98440, 2017, A1. Location in patent: Page/Page column 120
[3] Patent: WO2008/23161, 2008, A1. Location in patent: Page/Page column 119
[4] Patent: WO2011/75699, 2011, A2. Location in patent: Page/Page column 206
[5] Journal of Agricultural and Food Chemistry, 2015, vol. 63, # 31, p. 6883 - 6889

2-Amino-4-bromobenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-4-bromobenzamide Suppliers

China 48 India 1 Switzerland 2 United Kingdom 2 United States 9 Global 62
Synzis Biotechnology Co., Ltd
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15927555332; 19170067735
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416647786@QQ.COM
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China
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
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info@chemlin.com.cn
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China
ProdList
16075
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
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0539-6365991
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SuZhou ShiYa Biopharmaceuticals, Inc.
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Bide Pharmatech Ltd.
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400-164-7117 13681763483
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parabiochem
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Amadis Chemical Company Limited
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Aikon International Limited
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112253-70-0, 2-Amino-4-bromobenzamideRelated Search:

trimethylamine oxide

  • 2-Amino-4-bromobenzamide
  • 4-Bromoanthranilamide
  • Benzamide, 2-amino-4-bromo-
  • 112253-70-0