2-Bromo-6-methoxybenzonitrile
- Product Name
- 2-Bromo-6-methoxybenzonitrile
- CAS No.
- 1245647-50-0
- Chemical Name
- 2-Bromo-6-methoxybenzonitrile
- Synonyms
- 2-Bromo-6-methoxybenzonitrile;Benzonitrile, 2-bromo-6-methoxy-
- CBNumber
- CB52500020
- Molecular Formula
- C8H6BrNO
- Formula Weight
- 212.04
- MOL File
- 1245647-50-0.mol
2-Bromo-6-methoxybenzonitrile Property
- Boiling point:
- 310.9±27.0 °C(Predicted)
- Density
- 1.56±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- color
- Pale yellow
Safety
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B696603
- Product name
- 2-Bromo-6-methoxybenzonitrile
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- X9592
- Product name
- 2-Bromo-6-methoxybenzonitrile
- Packaging
- 250mg
- Price
- $81
- Updated
- 2021/12/16
- Product number
- X9592
- Product name
- 2-Bromo-6-methoxybenzonitrile
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- HCH0357650
- Product name
- 2-BROMO-6-METHOXYBENZONITRILE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.36
- Updated
- 2021/12/16
- Product number
- A122547
- Product name
- 2-Bromo-6-methoxybenzonitrile
- Purity
- 98%
- Packaging
- 250mg
- Price
- $16
- Updated
- 2021/12/16
2-Bromo-6-methoxybenzonitrile Chemical Properties,Usage,Production
Synthesis
1393739-62-2
1245647-50-0
The general procedure for the synthesis of 2-bromo-6-methoxybenzonitrile using the compound (CAS:1393739-62-2) as starting material was as follows: 1-(azidomethyl)-4-methoxybenzene (8a) (81 mg, 0.5 mmol) was dissolved in acetonitrile (0.5 mL) at 0 °C followed by the addition of iodobenzene dibenzoate (PhI(OAc)2) ( 483.1 mg, 1.5 mmol). A solution of tert-butyl hydroperoxide (tBuOOH) (5.0-6.0 M, dissolved in decane, 360 μL, 2.0 mmol) was slowly added dropwise over a period of 1 h under vigorous stirring. After dropwise addition, stirring of the reaction mixture was continued for 11 hours. Upon completion of the reaction, the target product 4-methoxybenzyl cyanide (9a) was purified by silica gel column chromatography using hexane/ethyl acetate (10:1) as eluent to give the target product 4-methoxybenzonitrile (9a) as a yellow oil (55.3 mg, 83% yield).
References
[1] Tetrahedron Letters, 2012, vol. 53, # 35, p. 4766 - 4769
2-Bromo-6-methoxybenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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