tert-Butyl 6-methylpiperidin-3-ylcarbamate

Product Name: tert-Butyl 6-methylpiperidin-3-ylcarbamate
CAS No.: 1150618-39-5
Chemical Name: tert-Butyl 6-methylpiperidin-3-ylcarbamate
Synonyms: EOS-61088;Ritlecitinib Impurity 3;3-(Boc-amino)-6-methylpiperidine;tert-Butyl 6-methylpiperidin-3-ylcarbamate;tert-butyl N-(6-methyl-3-piperidyl)carbamate;tert-butyl N-(6-methylpiperidin-3-yl)carbamate;(6-Methyl-piperidin-3-yl)-carbaMic acid tert-butyl ester;Carbamic acid, N-(6-methyl-3-piperidinyl)-, 1,1-dimethylethyl ester
CBNumber: CB52500611
Molecular Formula: C11H22N2O2
Formula Weight: 214.3
MOL File: 1150618-39-5.mol

More

Less

tert-Butyl 6-methylpiperidin-3-ylcarbamate Property

Density: 1.00
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
Appearance: Light yellow to brown Liquid
InChI: InChI=1S/C11H22N2O2/c1-8-5-6-9(7-12-8)13-10(14)15-11(2,3)4/h8-9,12H,5-7H2,1-4H3,(H,13,14)
InChIKey: NNMBHCRWGGSRBE-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)NC1CCC(C)NC1

More

Less

Safety

HS Code: 2933599590

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Matrix Scientific

Product number: 207668
Product name: tert-Butyl N-(6-methyl-3-piperidyl)carbamate
Packaging: 250.00mg
Price: $88
Updated: 2026/05/18

Matrix Scientific

Product number: 207668
Product name: tert-Butyl N-(6-methyl-3-piperidyl)carbamate
Packaging: 1.00g
Price: $223
Updated: 2026/05/18

Matrix Scientific

Product number: 207668
Product name: tert-Butyl N-(6-methyl-3-piperidyl)carbamate
Packaging: 5.00g
Price: $681
Updated: 2026/05/18

Synthonix

Product number: B8726
Product name: tert-Butyl (6-methylpiperidin-3-yl)carbamate
Purity: 95%
Packaging: 250mg
Price: $100
Updated: 2026/05/06

Synthonix

Product number: B8726
Product name: tert-Butyl (6-methylpiperidin-3-yl)carbamate
Purity: 95%
Packaging: 1g
Price: $230
Updated: 2026/05/06

More

Less

tert-Butyl 6-methylpiperidin-3-ylcarbamate Chemical Properties,Usage,Production

Synthesis

323578-37-6

1150618-39-5

Step 2. Synthesis of racemic-cis/trans-tert-butyl (6-methylpiperidin-3-yl) carbamate. Platinum(II) oxide (2.5 g) was added to a dry hydrogenation flask under argon protection. Subsequently, a solution of N-Boc-6-methyl-3-aminopyridine (33 g, 158.5 mmol) in acetic acid (300 mL) was added, and the resulting mixture was hydrogenated at 50 °C under 55 psi hydrogen pressure for 30 hours. The reaction was monitored by thin layer chromatography (TLC) (petroleum ether/ethyl acetate, 2:1) to confirm complete consumption of the feedstock. The reaction mixture was filtered and the filter cake was washed with methanol (50 mL x 2). The combined filtrates were concentrated under reduced pressure to afford tert-butyl (6-methylpiperidin-3-yl) carbamate (34 g, 100%) as a yellow oil (cis/trans ratio 2:1), which could be used in the subsequent steps without further purification.LC/MS analysis showed (M+H)+ of 215.2.

References

[1] Patent: US2015/158864, 2015, A1. Location in patent: Paragraph 0270
[2] Patent: WO2010/16005, 2010, A1. Location in patent: Page/Page column 135-136
[3] Patent: WO2016/196776, 2016, A2. Location in patent: Paragraph 001090
[4] Patent: WO2012/148775, 2012, A1. Location in patent: Page/Page column 114

tert-Butyl 6-methylpiperidin-3-ylcarbamate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

tert-Butyl 6-methylpiperidin-3-ylcarbamate Suppliers

China 63 India 2 United Kingdom 1 United States 5 Global 71

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9340
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

Porse Fine Chemical Co.,LTD

Tel: 20-66003216 18666003216
Fax: +86-20-28069063
Email: info@porsefinechemical.com
Country: China
ProdList: 1958
Advantage: 62

Taizhou Yikang Chemical Co., Ltd.

Tel: 0576-88501337 18057652630
Fax: +86-576-88501337
Email: sales@yikangchemicals.com
Country: China
ProdList: 272
Advantage: 58

Zhengzhou TRIZ Pharmaceutical Technology Co., Ltd.

Tel: 19943855286
Fax: 0371-53392065
Email: triz-4@trizpharma.cn
Country: China
ProdList: 1936
Advantage: 56

Shanghai Synteam Biochem CO.,ltd

Tel: +86-021-58380978 13482386415
Fax: 021-58380978
Email: info@systeambc.com
Country: China
ProdList: 898
Advantage: 50

Shanghai Jovan Biochemical Technology Co. Ltd.

Tel: +86-021-61654350
Fax: +86-021-61654350
Email: 1245958370@qq.com
Country: China
ProdList: 2982
Advantage: 50

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 7250
Advantage: 58

Shanghai Mayzem Pharmtech Co., Ltd.

Tel: 18501708306; 18501708306
Fax: 021-68362870
Email: sales@mayzem.com
Country: China
ProdList: 518
Advantage: 56

1150618-39-5, tert-Butyl 6-methylpiperidin-3-ylcarbamateRelated Search:

TERT-BUTYL N-[(1-BENZYL-4-PIPERIDINYL)METHYL]CARBAMATE (2-AMINO-4-FLUORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER tert-butyl (pyrrolidin-3-yl)methylcarbamate Carbamic acid, (6-methyl-3-pyridinyl)-, 1,1-dimethylethyl ester (9CI)

tert-Butyl 6-methylpiperidin-3-ylcarbamate

(6-Methyl-piperidin-3-yl)-carbaMic acid tert-butyl ester

tert-butyl N-(6-methyl-3-piperidyl)carbamate

EOS-61088

Carbamic acid, N-(6-methyl-3-piperidinyl)-, 1,1-dimethylethyl ester

3-(Boc-amino)-6-methylpiperidine

Ritlecitinib Impurity 3

tert-butyl N-(6-methylpiperidin-3-yl)carbamate

1150618-39-5