tert-butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate

Product Name: tert-butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate
CAS No.: 871726-73-7
Chemical Name: tert-butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate
Synonyms: 6-BOC-2,4,5,7-Tetrahydro-pyrazolo[3,4-c]pyridine;6-Boc-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine;6-Boc-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine;tert-Butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H);tert-butyl 1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-6-carboxylate;6H-Pyrazolo[3,4-c]pyridine-6-carboxylic acid, 1,4,5,7-tetrah...;tert-Butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxyl;t-Butyl 4,5-Dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate;tert-butyl 1,4,5,7-tetrahydropyrazolo[3,4-c]pyridine-6-carboxylate;tert-butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate
CBNumber: CB52503425
Molecular Formula: C11H17N3O2
Formula Weight: 223.27
MOL File: 871726-73-7.mol

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tert-butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate Property

Boiling point:: 388.0±42.0 °C(Predicted)
Density: 1.200
storage temp.: 2-8°C
pka: 14.93±0.20(Predicted)
Appearance: White to light yellow Solid
InChI: InChI=1S/C11H17N3O2/c1-11(2,3)16-10(15)14-5-4-8-6-12-13-9(8)7-14/h6H,4-5,7H2,1-3H3,(H,12,13)
InChIKey: XSHYMCSSTAWZOW-UHFFFAOYSA-N
SMILES: C1N(C(OC(C)(C)C)=O)CCC2C=NNC1=2

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TRC

Product number: B902670
Product name: tert-Butyl4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B902670
Product name: tert-Butyl4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate
Packaging: 100mg
Price: $65
Updated: 2021/12/16

TRC

Product number: B902670
Product name: tert-Butyl4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate
Packaging: 500mg
Price: $285
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB154078
Product name: tert-Butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate
Packaging: 250mg
Price: $300
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-0BY
Product name: tert-Butyl 1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridine-6-carboxylate
Packaging: 1g
Price: $420
Updated: 2021/12/16

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tert-butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate Chemical Properties,Usage,Production

Synthesis

871726-72-6

871726-73-7

General procedure for the synthesis of tert-butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate from tert-butyl 4-((dimethylamino)methylene)-3-oxopiperidine-1-carboxylate: to a stirred tert-butyl 4-((dimethylamino)methylene)-3-oxopiperidine-1-carboxylate (1.0 g, 4 mmol) ethanol (EtOH. 10 mL) solution was added to hydrazine hydrate (376 mg, 10 mmol). The reaction mixture was stirred at 80 °C for 16 h until liquid chromatography-mass spectrometry (LCMS) analysis showed that the reaction was complete. After completion of the reaction, the mixture was concentrated and the residue was diluted with water (30 mL) and extracted with ethyl acetate (EA, 3 x 30 mL). The organic phases were combined, washed with brine (20 mL), dried over anhydrous sodium sulfate (Na2SO4) and concentrated. The resulting residue was used directly in the next step of the reaction (810 mg, 90% yield).LCMS data: 224.1 (M + 1), 114.1 (M + 1-100), 168.1 (M + 1-56).

References

[1] Patent: WO2014/100695, 2014, A1. Location in patent: Paragraph 00413

tert-butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate Suppliers

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View Lastest Price from tert-butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate manufacturers

Career Henan Chemical Co

Product: tert-butyl 1,4,5,7-tetrahydropyrazolo[3,4-c]pyridine-6-carboxylate 871726-73-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2020-02-05

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871726-73-7