2-oxa-6-azaspiro[3.4]octane
- Product Name
- 2-oxa-6-azaspiro[3.4]octane
- CAS No.
- 220290-68-6
- Chemical Name
- 2-oxa-6-azaspiro[3.4]octane
- Synonyms
- 2-oxa-7-azaspiro[3.4]octane;2-oxa-6-azaspiro[3.4]octane;2-Oxa-6-azaspiro[3.4]octa...;2-Oxa-6-azaspiro[3.4]octane,95%;2-Oxa-6-azaspiro[3.4]octane (9CI, ACI);2-oxa-6-azaspiro[3.4]octane, hemioxalate salt
- CBNumber
- CB52506037
- Molecular Formula
- C6H11NO
- Formula Weight
- 113.16
- MOL File
- 220290-68-6.mol
2-oxa-6-azaspiro[3.4]octane Property
- Boiling point:
- 187℃
- Density
- 1.08
- Flash point:
- 63°(145°F)
- storage temp.
- 2-8°C(protect from light)
- pka
- 10.55±0.20(Predicted)
- Water Solubility
- Soluble in water.
- InChI
- InChI=1S/C6H11NO/c1-2-7-3-6(1)4-8-5-6/h7H,1-5H2
- InChIKey
- ZHAIMJRKJKQNQI-UHFFFAOYSA-N
- SMILES
- C1C2(CCNC2)CO1
Safety
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H57579
- Product name
- 2-Oxa-6-azaspiro[3.4]octane, 95%
- Packaging
- 250mg
- Price
- $324.65
- Updated
- 2024/03/01
- Product number
- H57579
- Product name
- 2-Oxa-6-azaspiro[3.4]octane, 95%
- Packaging
- 500mg
- Price
- $592.65
- Updated
- 2024/03/01
- Product number
- 285953
- Product name
- 2-Oxa-6-azaspiro[3.4]octane
- Packaging
- 25mg
- Price
- $359
- Updated
- 2021/12/16
- Product number
- O990125
- Product name
- 2-Oxa-6-Azaspiro[3.4]Octane
- Packaging
- 10mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 4H31-1-10
- Product name
- 2-Oxa-6-azaspiro[3.4]octane
- Packaging
- 250mg
- Price
- $295
- Updated
- 2021/12/16
2-oxa-6-azaspiro[3.4]octane Chemical Properties,Usage,Production
Uses
2-Oxa-6-azaspiro[3.4]octane is involved in the preparation of azaspirocycle or azetidine substituted 4-anilinoquinazoline derivatives, which exhibits epidermal growth factor receptor (EGFR) inhibitory activities.
Application
2-Oxa-6-Azaspiro[3.4]Octane Hydrochloride may be useful in the preparation of aminocyanopyridine derivatives for the prevention or treatment of cancer or inflammatory diseases.
Synthesis
Tert-butyl 2-oxa-6-azaspiro[3.4]octane-6-carboxylate (86mg, 0.4mmol) was dissolved in dichloromethane (1mL), trifluoroacetic acid (2mL) was added to the system at room temperature, and the reaction solution was heated at 60°C for 2h. The reaction solution was cooled to room temperature and concentrated under reduced pressure to obtain crude product 2-oxa-6-azaspiro[3.4]octane.
2-oxa-6-azaspiro[3.4]octane Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-oxa-6-azaspiro[3.4]octane manufacturers
- Product
- 2-oxa-6-azaspiro[3.4]octane 220290-68-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-99.9%
- Supply Ability
- 100kg
- Release date
- 2020-01-10