ChemicalBook > CAS DataBase List > 2-oxa-6-azaspiro[3.4]octane

2-oxa-6-azaspiro[3.4]octane

Product Name
2-oxa-6-azaspiro[3.4]octane
CAS No.
220290-68-6
Chemical Name
2-oxa-6-azaspiro[3.4]octane
Synonyms
2-oxa-7-azaspiro[3.4]octane;2-oxa-6-azaspiro[3.4]octane;2-Oxa-6-azaspiro[3.4]octa...;2-Oxa-6-azaspiro[3.4]octane,95%;2-Oxa-6-azaspiro[3.4]octane (9CI, ACI);2-oxa-6-azaspiro[3.4]octane, hemioxalate salt
CBNumber
CB52506037
Molecular Formula
C6H11NO
Formula Weight
113.16
MOL File
220290-68-6.mol
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2-oxa-6-azaspiro[3.4]octane Property

Boiling point:
187℃
Density 
1.08
Flash point:
63°(145°F)
storage temp. 
2-8°C(protect from light)
pka
10.55±0.20(Predicted)
Water Solubility 
Soluble in water.
InChI
InChI=1S/C6H11NO/c1-2-7-3-6(1)4-8-5-6/h7H,1-5H2
InChIKey
ZHAIMJRKJKQNQI-UHFFFAOYSA-N
SMILES
C1C2(CCNC2)CO1
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Safety

HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H57579
Product name
2-Oxa-6-azaspiro[3.4]octane, 95%
Packaging
250mg
Price
$324.65
Updated
2024/03/01
Alfa Aesar
Product number
H57579
Product name
2-Oxa-6-azaspiro[3.4]octane, 95%
Packaging
500mg
Price
$592.65
Updated
2024/03/01
Usbiological
Product number
285953
Product name
2-Oxa-6-azaspiro[3.4]octane
Packaging
25mg
Price
$359
Updated
2021/12/16
TRC
Product number
O990125
Product name
2-Oxa-6-Azaspiro[3.4]Octane
Packaging
10mg
Price
$65
Updated
2021/12/16
SynQuest Laboratories
Product number
4H31-1-10
Product name
2-Oxa-6-azaspiro[3.4]octane
Packaging
250mg
Price
$295
Updated
2021/12/16
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2-oxa-6-azaspiro[3.4]octane Chemical Properties,Usage,Production

Uses

2-Oxa-6-azaspiro[3.4]octane is involved in the preparation of azaspirocycle or azetidine substituted 4-anilinoquinazoline derivatives, which exhibits epidermal growth factor receptor (EGFR) inhibitory activities.

Application

2-Oxa-6-Azaspiro[3.4]Octane Hydrochloride may be useful in the preparation of aminocyanopyridine derivatives for the prevention or treatment of cancer or inflammatory diseases.

Synthesis

Tert-butyl 2-oxa-6-azaspiro[3.4]octane-6-carboxylate (86mg, 0.4mmol) was dissolved in dichloromethane (1mL), trifluoroacetic acid (2mL) was added to the system at room temperature, and the reaction solution was heated at 60°C for 2h. The reaction solution was cooled to room temperature and concentrated under reduced pressure to obtain crude product 2-oxa-6-azaspiro[3.4]octane.

2-oxa-6-azaspiro[3.4]octane Preparation Products And Raw materials

Raw materials

Preparation Products

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2-oxa-6-azaspiro[3.4]octane Suppliers

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View Lastest Price from 2-oxa-6-azaspiro[3.4]octane manufacturers

Career Henan Chemical Co
Product
2-oxa-6-azaspiro[3.4]octane 220290-68-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98%-99.9%
Supply Ability
100kg
Release date
2020-01-10

220290-68-6, 2-oxa-6-azaspiro[3.4]octaneRelated Search:

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