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2,3-Diamino-4-bromopyridine

Product Name
2,3-Diamino-4-bromopyridine
CAS No.
1232431-75-2
Chemical Name
2,3-Diamino-4-bromopyridine
Synonyms
4-broMopyridine-2,3-diaMine;4-broMopyridine-2;4-BroMo-2,3-diaMinopyridine;2,3-Diamino-4-bromopyridine;4-Bromo-2,3-pyridinediamine;2,3-Pyridinediamine, 4-bromo-
CBNumber
CB52507089
Molecular Formula
C5H6BrN3
Formula Weight
188.03
MOL File
1232431-75-2.mol
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2,3-Diamino-4-bromopyridine Property

Melting point:
154-155 °C
Boiling point:
341.6±37.0 °C(Predicted)
Density 
1.818±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
powder
pka
5.68±0.47(Predicted)
color 
Grey/purple/brown
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B416733
Product name
4-Bromopyridine-2,3-diamine
Packaging
100mg
Price
$65
Updated
2021/12/16
TRC
Product number
B416733
Product name
4-Bromopyridine-2,3-diamine
Packaging
500mg
Price
$220
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
D13409
Product name
2,3-Diamino-4-bromopyridine
Purity
95%
Packaging
1g
Price
$100
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0365887
Product name
4-BROMOPYRIDINE-2,3-DIAMINE
Purity
95.00%
Packaging
5MG
Price
$505.26
Updated
2021/12/16
Matrix Scientific
Product number
188897
Product name
4-Bromopyridine-2,3-diamine
Packaging
1g
Price
$510
Updated
2021/12/16
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2,3-Diamino-4-bromopyridine Chemical Properties,Usage,Production

Synthesis

1305317-30-9

1232431-75-2

General procedure for the synthesis of 4-bromopyridine-2,3-diamine from 4-bromo-2-nitropyridin-3-amine: 4-bromo-2-nitropyridin-3-amine (1 g, 4.59 mmol) was dissolved in a solvent mixture of EtOH (20 mL) and water (5 mL) under stirring. To this solution, tin(IV) chloride (3.00 g, 11.52 mmol) was added slowly with the addition time controlled at 1 min. The reaction mixture was heated to 90°C and stirred at this temperature for 2 hours. After the reaction was completed, the mixture was cooled to room temperature and then carefully poured into saturated sodium bicarbonate solution (50 mL). The reaction mixture was extracted with dichloromethane (DCM, 2 x 100 mL). The organic phases were combined and washed sequentially with water (100 mL) and brine (100 mL). The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 4-bromopyridine-2,3-diamine (460 mg, 2.446 mmol, 53% yield) as a light brown solid. The resulting compound did not require further purification and could be used directly in the next step of the reaction.LCMS (ESI) m/z 187.9 [M+H]+ (calculated value C5H7BrN3, 187.91; measured value: 187.91).LC/MS retention time (Method C) tR=0.52 min.

References

[1] Synthesis, 2011, # 5, p. 794 - 806
[2] Patent: WO2017/59080, 2017, A1. Location in patent: Page/Page column 35; 111; 112

2,3-Diamino-4-bromopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-Diamino-4-bromopyridine Suppliers

China 68 Germany 1 India 1 United States 5 Global 75
Alchem Pharmtech,Inc.
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8485655694
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sales@alchempharmtech.com
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United States
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63687
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Aladdin Scientific
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tp@aladdinsci.com
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United States
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57505
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Synthonix Inc
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info@synthonix.com
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United States
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6872
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SynQuest Laboratories, Inc.
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info@synquestlabs.com
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United States
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6871
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Frontier Scientific, Inc.
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Email
sales@frontiersci.com
Country
United States
ProdList
6222
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View Lastest Price from 2,3-Diamino-4-bromopyridine manufacturers

Shanghai kingmorn biotechnology Co.,LTD.
Product
2,3-Diamino-4-bromopyridine 1232431-75-2
Price
US $0.00-0.00/g
Min. Order
1g
Purity
97%
Supply Ability
>10kg
Release date
2021-07-15

1232431-75-2, 2,3-Diamino-4-bromopyridineRelated Search:


  • 2,3-Diamino-4-bromopyridine
  • 4-BroMo-2,3-diaMinopyridine
  • 4-broMopyridine-2,3-diaMine
  • 4-broMopyridine-2
  • 2,3-Pyridinediamine, 4-bromo-
  • 4-Bromo-2,3-pyridinediamine
  • 1232431-75-2